This study focuses on finding the best medication for rapid sequence induction, which is a medical procedure used to quickly make patients unconscious before surgery when there is a risk of stomach contents entering the lungs. The study compares three different approaches: using propofol alone (a commonly used anesthetic medication), using ketamine alone, or using a combination of both medications.
The purpose of this research is to determine which of these medication options works best for safely putting patients to sleep and placing a breathing tube, while maintaining stable blood pressure. The medications will be given through an intravenous injection, which means they are delivered directly into a vein. The study will look at how well each medication option works in helping doctors successfully place the breathing tube on the first try without causing a dangerous drop in blood pressure.
During the study, patients will receive one of the three medication options before their planned surgery. The medical team will monitor vital signs including blood pressure, heart rate, and oxygen levels for 10 minutes after giving the medication. Patients will also be checked for any side effects while in the recovery room after surgery and for up to one week afterward.



France