KarXT is an investigational medication being studied for treating psychosis symptoms (such as hallucinations and delusions) in people with Alzheimer’s disease. It is designed to help reduce psychiatric symptoms that can occur in Alzheimer’s patients without causing some of the common side effects associated with current antipsychotic medications.

The trial also includes a placebo, which is an inactive substance used to compare the effects of the actual medication.

Psychosis Associated with Alzheimer’s Disease – A condition that occurs in some people with Alzheimer’s disease where patients experience hallucinations and delusions. Hallucinations involve seeing, hearing, or feeling things that are not actually present, while delusions are false beliefs that persist despite evidence to the contrary. This condition typically develops as Alzheimer’s disease progresses, causing significant changes in perception and thought processes. The symptoms can include seeing nonexistent people or objects, hearing voices, or having persistent unfounded suspicions about family members or caregivers. These psychotic symptoms can fluctuate in intensity over time and may become more pronounced in the later afternoon or evening.