Dasatinib is a medication that is typically used to treat certain types of cancer. In this trial, it is being studied for its potential to help improve bone health in people with low bone mass. Researchers are interested in seeing if dasatinib can help reduce the breakdown of bone, which is a common problem in conditions like osteoporosis.

Quercetin is a natural substance found in many fruits and vegetables. It is being tested in this trial to see if it can work together with dasatinib to improve bone health. Quercetin is thought to have properties that might help protect bones from damage and support their strength.

Nicotinamide Riboside is a form of vitamin B3 that is being studied for its potential benefits on bone health. In this trial, researchers are exploring whether nicotinamide riboside can help reduce bone loss in people with low bone mass. It is believed to support the health of cells, which might contribute to stronger bones.

Osteoporosis – Osteoporosis is a condition characterized by weakened bones, which increases the risk of fractures. It occurs when the creation of new bone doesn’t keep up with the removal of old bone. Over time, bones become porous and fragile. This disease often progresses silently without symptoms until a fracture occurs. Common fracture sites include the hip, spine, and wrist. As the disease advances, even minor stresses like bending over or coughing can cause fractures.

Osteopenia – Osteopenia is a condition where bone mineral density is lower than normal but not low enough to be classified as osteoporosis. It is considered a precursor to osteoporosis and indicates a risk of developing the more severe condition. The progression involves a gradual decrease in bone density, which can lead to increased fragility. Unlike osteoporosis, osteopenia may not always result in fractures. However, it serves as a warning sign for potential future bone health issues. Regular monitoring of bone density is important to track its progression.