Zoledronic Acid is a medication used in this clinical trial to see if it helps improve the healing of tendons after surgery. It is given through an intravenous infusion, which means it is delivered directly into the bloodstream. The study aims to find out if using zoledronic acid can make the tendons heal better after they have been repaired during surgery for chronic rotator cuff injuries. The researchers will use imaging techniques to check the condition of the tendons at different times after the surgery to see if the medication has a positive effect.

Trauma (rupture of a tendon) – This condition occurs when a tendon, which connects muscle to bone, is torn or ruptured. It often results from a sudden injury or overuse, leading to pain, swelling, and difficulty moving the affected area. The severity of the rupture can vary, with partial tears causing less dysfunction than complete tears. Over time, the body attempts to heal the tendon, but the process can be slow and may not fully restore the tendon’s original strength or flexibility. Recovery often involves a combination of rest, physical therapy, and gradual return to activity. In some cases, surgical intervention may be necessary to repair the tendon.

Osteoporosis – This is a condition characterized by weakened bones that become fragile and more likely to fracture. It develops gradually over many years, often without symptoms until a fracture occurs. The disease is most common in older adults, particularly postmenopausal women, due to changes in hormone levels that affect bone density. As bones lose density, they become porous and brittle, increasing the risk of breaks from minor falls or even normal activities. The progression of osteoporosis can lead to a decrease in height, a stooped posture, and persistent back pain due to vertebral fractures. Maintaining bone health through diet and lifestyle is crucial in managing the condition.