This study focuses on patients with Multiple Myeloma that has returned or become resistant to previous treatments. Multiple Myeloma is a type of blood cancer that affects plasma cells, which are cells in the bone marrow that help fight infections. The study will test a combination of two medications: isatuximab and pegenzileukin, which will be given through intravenous infusion (delivery directly into a vein).
The purpose of this research is to evaluate how well these medications work together in treating patients whose cancer has previously been treated with other therapies. The study is divided into two parts. The first part will determine the right dose of the medications when used together, while the second part will test how effective this combination is in treating the cancer.
During the study, participants will receive both medications through regular infusions. The treatment will continue as long as it appears to be helping and the side effects are manageable. Throughout the study, doctors will monitor participants’ health status and how well the cancer responds to treatment. They will also assess how the treatment affects participants’ quality of life.



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