Elexacaftor is a medication used to treat cystic fibrosis. It works by helping abnormal proteins function better in people with specific genetic mutations that cause cystic fibrosis. This medication helps improve lung function and breathing.

Tezacaftor is another medication used in treating cystic fibrosis. It works together with other medications to help the proteins in the body function more normally. This helps thin the mucus in the lungs of people with cystic fibrosis.

Ivacaftor is a medication that helps improve the function of a specific protein in people with cystic fibrosis. It helps improve breathing and lung function by helping to maintain proper salt and water balance in the lungs.

These three medications are used together as a combination therapy to provide better treatment outcomes for people with cystic fibrosis. The combination helps improve lung function and breathing more effectively than using any of these medications alone.

Cystic Fibrosis – A genetic disorder that affects cells producing mucus, sweat, and digestive fluids. The condition causes these fluids to become thick and sticky instead of thin and slippery. This buildup of thick, sticky secretions can clog various tubes and ducts throughout the body, particularly in the lungs and pancreas. The disease primarily affects the respiratory and digestive systems, causing recurring lung infections and difficulty absorbing nutrients from food. People with cystic fibrosis inherit a defective gene from both parents that affects a protein regulating salt and water movement in cells.