Paediatric rheumatology and autoinflammatory disease
Clinical research in juvenile idiopathic arthritis and recurrent pericarditis includes treatment strategies for disease control, flare prevention, and targeted anti-inflammatory therapy in children and adolescents.
- Juvenile idiopathic arthritis
- Recurrent pericarditis
- PAPA syndrome
- IL-1 blockade
Work in this area also covers biomarker-informed treatment decisions and the management of inflammatory conditions that are resistant to standard anti-rheumatic therapy.
Pediatric oncology and cellular immunotherapy
Research activity includes high-risk neuroblastoma and complex post-transplant oncologic care, with interest in immune-based strategies and transplant-supported treatment pathways.
- High-risk neuroblastoma
- Haploidentical stem cell transplantation
- Donor NK-cell immunotherapy
- Anti-GD2 monoclonal antibody therapy
The sponsor is also involved in pediatric hematologic oncology settings where immune reconstitution and relapse control are central concerns.
Transplant medicine and viral complications
Studies address allogeneic hematopoietic stem cell transplantation complicated by resistant viral reactivation, with attention to infections affecting immunocompromised children and young adults.
- CMV reactivation
- EBV reactivation
- Adenovirus infection
- Virus-specific T lymphocytes
This research area extends to difficult-to-treat post-transplant infections and immune-based approaches for viral control.
Cystic fibrosis and respiratory pharmacology
Clinical work in cystic fibrosis focuses on treatment-related pharmacology and the use of combination therapies relevant to chronic pulmonary disease.
- Cystic fibrosis
- CFTR modulator therapy
- Drug pharmacokinetics
These studies reflect interest in optimizing therapeutic management for children with genetic respiratory disease.
Pediatric anesthesia and perioperative care
Research spans neonatal and pediatric anesthesia, including analgesia for cesarean section, neurodevelopmental outcomes after early-life surgery, and monitoring of neuromuscular recovery.
- Elective cesarean section
- General anesthesia
- Neuromuscular monitoring
- Neurocognitive development
Additional activity includes perioperative management for children under 2 years of age and optimization of anesthetic care in surgical settings.
