This clinical trial focuses on treating severe acute trauma-related pain in children who have suffered limb injuries. The study compares two pain medications: sufentanil and ketamine, both given as nasal sprays. These medications are typically used in hospitals to manage severe pain, but in this study, they will be administered through the nose instead of traditional injection methods.
The main purpose is to determine which of these two medications works better for pain relief in children who come to the emergency department with severe limb injuries such as suspected fractures, severe sprains, dislocations, or joint trauma. The medications will be given as a single dose through a nasal spray, and pain levels will be monitored for up to 30 minutes after administration.
During the study, children will receive either intranasal sufentanil or intranasal ketamine. Other pain relief options like EMLA cream (a numbing cream), naloxone (a medication that reverses opioid effects), and Entonox (a mixture of nitrous oxide and oxygen for pain relief) will be available if needed. The children’s pain levels, drowsiness, and any side effects will be monitored regularly throughout the treatment period.
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