A study on the use of vancomycin and a drug combination for treating infections in children through continuous antibiotic infusion.

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What is this study about?

This study is being conducted to evaluate the effectiveness and safety of continuous antibiotic infusion in children with an Infection. An infection occurs when harmful germs, such as bacteria, enter the body and cause illness. The study focuses on comparing different ways of delivering medication to see which approach works best for treating these conditions.

The medications being studied include cloxacillin, benzylpenicillin, piperacillin, tazobactam, and vancomycin. These are types of antibiotics, which are medicines used to kill or stop the growth of bacteria. During the study, these drugs will be administered through an intravenous infusion, which is a method where the medicine is delivered directly into a vein through a tube to ensure it enters the bloodstream steadily.

The research involves a method called continuous infusion, meaning the medication is given at a constant rate over a 24-hour period rather than in separate doses. Participants will receive these treatments to help determine the best way to manage bacterial illnesses in a hospital setting.

Who Can Join the Study?

  • The child must require treatment with intravenous (IV) antibiotics, which is medicine delivered directly into a vein through a tube.
  • The child must be clinically stable, meaning their medical condition is steady and not rapidly changing or worsening.
  • The child must not require staying in the hospital for their care.
  • A pump or cassette (the device used to deliver the medicine steadily) must be able to be changed at either the hospital or at home.
  • The people looking after the child must be able to contact the hospital if any help is needed.
  • The clinical diagnosis, which is the identification of the illness by a doctor, must be certain.
  • The child must not have any allergies, or harmful reactions, to the specific antibiotic being used.
  • The continuous antibiotic infusion, which is the process of giving medicine through a vein at a steady rate for a long time, must either not have started yet or must have started less than 24 hours before joining the study.

Who Cannot Join the Study?

  • The child cannot carry the infusion pump, which is a small medical device used to deliver medicine into the body at a steady rate.
  • The child is required to stay in the hospital for observation or for any other medical reason.
  • The diagnosis, which is the identification of the specific illness or condition the child has, is not clearly known.
  • The child has an infectious disease, which is an illness caused by germs like bacteria or viruses that can spread to others.

Where you can join this trial?

Verified and Recommended Sites

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Verified Sites

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Other Sites

Site Name City Country Status
Pirkanmaan hyvinvointialue Tampere Finland

Want to learn more about this study or check if you can participate? Contact us.

Trial status

Country Status Recruitment Start
Finland Finland
Recruiting
01.02.2026

Trial locations

Cloxacillin is an antibiotic medication given through a vein to help fight certain types of bacterial infections.

Benzylpenicillin is an antibiotic medication given through a vein to treat various bacterial infections.

Piperacillin/Tazobactam is a combination antibiotic medication given through a vein to treat serious bacterial infections.

Vancomycin is an antibiotic medication given through a vein to treat severe infections caused by specific types of bacteria.

Investigated diseases:

Infectious disease – An infectious disease is a condition caused by harmful organisms such as bacteria, viruses, fungi, or parasites entering the body. These organisms can multiply within the host and interfere with normal bodily functions. The disease typically progresses as the pathogens spread through tissues or the bloodstream. As the infection develops, the body may react with symptoms like fever or inflammation. The severity and speed of progression often depend on the type of organism involved and the person’s immune response.

Trial ID:
2025-522809-38-00
Trial Phase:
Therapeutic confirmatory (Phase III)

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