Vrije Universiteit Brussel

Chronic Pain and Spinal Pain Syndromes

Research activity includes chronic lower back pain and Persistent Spinal Pain Syndrome Type II, with attention to pain-related disability and functional outcomes after pain-focused interventions.

  • Axial pain
  • Disability in chronic pain
  • Pain medication tapering

Clinical interest also extends to treatment pathways for patients living with ongoing spinal pain and long-term pain-related impairment.

Cancer Pain and Palliative Symptom Control

The sponsor supports studies in severe refractory cancer pain, including approaches aimed at improving analgesia when standard pain management is insufficient.

  • Refractory pain
  • Cancer-related pain
  • Pain pump therapy

This area reflects a focus on complex pain syndromes in oncology settings, where symptom relief and daily functioning are central concerns.

Neuroscience and Fatigue Mechanisms

Another research theme examines the role of brain neurotransmission in fatigue, linking neurobiological pathways with symptom burden and patient experience.

  • Neurotransmitters
  • Brain neurotransmission
  • Fatigue biology

Interest in this field connects central nervous system processes with persistent symptoms that can affect quality of life across multiple conditions.

Trials funded by the sponsor also evaluate health-related quality of life, with emphasis on how pain and fatigue influence daily functioning, disability, and patient-reported well-being.

  • Patient-reported outcomes
  • Functional disability
  • Quality of life assessment

This area spans both pain and symptom research, capturing the broader impact of treatment on lived experience.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Opioid Detoxification Using Buprenorphine, Naloxone, and Oxycodone for Patients with Persistent Spinal Pain Syndrome Type II

    Recruiting

    3 1 1 1
    Investigated diseases:
    Belgium
  • Comparing ziconotide and a drug combination to standard medical management for patients with severe cancer pain

    Not yet recruiting

    3 1 1 1
    Investigated diseases:
    Belgium