University Of Cincinnati College Of Medicine

Stroke and Acute Haemorrhagic Neurology

Clinical research is centered on acute haemorrhagic stroke, with a focus on intracerebral hemorrhage and emergency treatment for spontaneous bleeding in the brain.

  • Acute spontaneous intracerebral hemorrhage
  • Functional recovery after stroke
  • Disability outcomes measured by the modified Rankin Scale

The research activity is directed toward early intervention in patients with life-threatening brain hemorrhage, with attention to neurological recovery and dependence in daily functioning.

Hemostatic and Coagulation Therapy

Therapeutic interest includes recombinant Factor VIIa as a treatment approach for controlling bleeding within the brain and limiting hematoma expansion.

  • Recombinant Factor VIIa
  • Coagulation factor treatment
  • Bleeding control in acute brain injury

This area reflects a strong focus on hemostatic therapy for urgent neurological conditions where rapid stabilization of hemorrhage is clinically important.

Emergency Neurologic Care

Research activity emphasizes treatment delivered in the earliest window after symptom onset, supporting urgent care pathways for patients with sudden brain hemorrhage.

  • Time-sensitive intervention
  • Emergency stroke management
  • Early treatment of intracranial bleeding

The clinical focus is on patients presenting shortly after onset, where rapid therapeutic action may influence neurological outcome.

Neuroimaging and Patient Stratification

Interest extends to baseline imaging features used in acute stroke care, including CTA findings such as the spot sign for identifying patients with active bleeding risk.

  • Computed tomography angiography (CTA)
  • Spot sign identification
  • Risk stratification in hemorrhagic stroke

These imaging-related elements support clinical decision-making in hemorrhagic stroke and help define the most relevant patient groups for treatment.

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Matched clinical trials

  • Study on Eptacog Alfa for Treating Acute Hemorrhagic Stroke in Patients with Brain Bleeding

    Recruiting

    3 1 1
    Investigated drugs:
    Germany Spain