Oncology and Molecular Imaging
Universitair Ziekenhuis Gent supports research in oncology with a strong focus on imaging-based assessment and treatment selection across several malignancies, including metastatic non-small-cell lung cancer, hepatocellular carcinoma, thyroid carcinoma, head and neck squamous cell carcinoma, glioblastoma, breast cancer, and oligorecurrent prostate cancer.
- Positron emission tomography and tumor staging
- Prostate-specific membrane antigen-directed imaging
- Radiotherapy and systemic treatment strategies
- Immunotherapy in advanced solid tumors
Its research activity also includes imaging-guided evaluation of metastatic and recurrent disease, with interest in peritoneal metastases and response assessment in advanced cancer settings.
Inflammatory and Autoimmune Diseases
The sponsor is active in rheumatology and dermatology, with trials in axial spondyloarthritis, peripheral spondyloarthritis, and moderate-to-severe psoriasis, as well as symptom-focused care in rhinitis medicamentosa.
- Spondyloarthritis disease activity assessment
- Biologic treatment strategies
- Immunomodulating agents
- Inflammatory skin disease
Research in this area also covers imaging approaches to support treatment decisions and disease monitoring in chronic immune-mediated disorders.
Cardiovascular and Infectious Diseases
Cardiology studies include coronary artery disease after percutaneous coronary intervention, while infectious disease research spans bacterial infections, mycoses, systemic infections, and HIV.
- Secondary prevention in coronary disease
- Antimicrobial therapy in critical illness
- HIV treatment switching
- Bloodstream and intra-abdominal infection management
The portfolio also includes work on optimizing antimicrobial exposure in critically ill patients and evaluating treatment strategies in viral and bacterial disease.
Reproductive, Perinatal, and Neonatal Care
The sponsor’s clinical research extends to subfertility, assisted reproductive technology, fertility preservation, and neonatal care, including management of hemodynamically stable term and preterm neonates requiring intubation.
- Ovarian stimulation strategies
- Fertility preservation and embryo development
- Neonatal intubation support
- Premature and term newborn analgesia and sedation
These studies reflect interest in reproductive medicine, perinatal pharmacology, and procedural care in newborns.
Transplantation, Cellular Therapy, and Neuropsychiatry
Additional research areas include allogeneic hematopoietic stem cell transplantation, CAR-T cell therapy, and treatment-resistant depression, alongside hospital-based evaluation of psilocybin-assisted psychotherapy.
- Fludarabine-based lymphodepletion
- Cellular therapy support in hematologic malignancy
- Psychiatric intervention for resistant depression
- Transplant conditioning and pharmacokinetics
The sponsor also maintains interest in treatment-related drug exposure and supportive care in complex hematology and mental health settings.
