Hematology and Cell Therapy
Clinical research includes acute myeloid leukemia, myelodysplastic neoplasms, chronic lymphocytic leukemia, lymphoma, and acute lymphoblastic leukemia, with activity across relapsed, refractory, and post-transplant settings.
- Allogeneic stem cell transplantation
- B-cell malignancies
- Minimal residual disease
- Leukemia vaccination
Research also covers fusion-driven sarcomas, fibrolamellar hepatocellular carcinoma, and immunotherapy-based approaches in advanced blood cancers and solid tumors.
Neuro-oncology and Neurology
Trials address glioblastoma, leptomeningeal disease, Parkinson disease, and disorders of brain injury and impaired vigilance, including hypoxic-ischemic encephalopathy and unresponsive wakefulness syndrome.
- Intrathecal immunotherapy
- Dopaminergic symptom control
- Neurorecovery
- Consciousness impairment
Additional work includes treatment strategies for chronic depression and neurological complications associated with severe illness.
Ophthalmology and Inherited Retinal Disease
Research activity includes acute central retinal artery occlusion, retinopathy of prematurity, achromatopsia, and retinitis pigmentosa, spanning both acquired and genetic causes of vision loss.
- Retinal ischemia
- Gene therapy
- Prematurity-related eye disease
- Visual function recovery
The portfolio reflects interest in restoring or preserving retinal function in paediatric and adult populations.
Pediatric, Neonatal, and Respiratory Care
Trials focus on extremely preterm infants, prematurity complications, and neonatal outcomes after asphyxia, with attention to respiratory support and neurodevelopment.
- Mechanical ventilation
- Therapeutic hypothermia
- Neurodevelopmental impairment
- Retinopathy of prematurity
Research also includes prevention and management of neonatal complications in intensive care settings.
Oncology, Metabolic Disease, and Infectious Disease
Studies extend to prostate cancer, rectal cancer, melanoma, and prediabetes, alongside work in malaria, COVID-19, and Staphylococcus aureus colonization.
- PSMA-targeted therapy
- Radiochemotherapy
- Glucose metabolism
- Vaccine immunogenicity
These trials encompass both cancer-directed treatment and prevention-oriented research in infectious and metabolic conditions.
