Cat Epithelium Extract

This article explores clinical trials investigating the use of Cat Epithelium Extract in allergy testing. Cat Epithelium Extract is being studied as a diagnostic tool for identifying allergies to cat dander. The trials aim to assess its effectiveness and safety when used in skin prick tests to detect cat allergies in patients with respiratory symptoms.

Table of Contents

What is CAT EPITHELIUM EXTRACT?

CAT EPITHELIUM EXTRACT is a medical product used in the diagnosis of cat allergies. It is derived from the outer layer of cat skin cells, known as the epithelium[1]. This extract contains proteins that commonly trigger allergic reactions in sensitive individuals.

Medical Use

The primary use of CAT EPITHELIUM EXTRACT is in skin prick tests, a common diagnostic procedure for identifying allergies. These tests help healthcare providers determine if a patient is allergic to cats[1].

Skin prick tests are typically used to diagnose conditions such as:

  • Allergic rhinitis (hay fever): Inflammation of the nasal passages causing symptoms like sneezing, runny nose, and congestion when exposed to cat allergens.
  • Allergic conjunctivitis: Inflammation of the eyes causing redness, itching, and tearing when exposed to cat allergens.
  • Asthma: In some cases, cat allergies can trigger or worsen asthma symptoms.

Administration

CAT EPITHELIUM EXTRACT is administered as a solution for skin-prick test. The procedure typically involves[1]:

  1. Applying a small drop of the extract on the skin, usually on the forearm or back.
  2. Gently pricking the skin through the drop with a sterile lancet.
  3. Waiting for about 15-20 minutes to observe any reaction.
  4. Measuring the size of any resulting wheal (a raised, itchy bump) to determine the severity of the allergy.

The maximum dose is typically 1 drop, applied topically (on the skin)[1].

Important Considerations

When undergoing a skin prick test with CAT EPITHELIUM EXTRACT, it’s important to note:

  • The test should be performed by a qualified healthcare professional.
  • Inform your doctor about any medications you’re taking, as some may interfere with the test results.
  • A positive result (wheal diameter ≥ 3 mm) indicates sensitization to cat allergens, but doesn’t necessarily mean you have a clinically relevant allergy[1].
  • Additional tests, such as blood tests for specific IgE antibodies, may be needed to confirm the diagnosis[1].

Ongoing Research

While CAT EPITHELIUM EXTRACT is primarily used as a diagnostic tool, ongoing research is exploring its potential use in immunotherapy for cat allergies. However, it’s important to note that the clinical trials mentioned in the provided data do not specifically focus on cat allergies or CAT EPITHELIUM EXTRACT[1][2][3]. These trials are investigating immunotherapy treatments for other types of allergies, such as birch pollen, grass pollen, and olive pollen allergies.

The inclusion of CAT EPITHELIUM EXTRACT in these trials’ data suggests that it may be used as a control or comparison in allergy studies, highlighting its importance in allergy research and diagnostics[1][2][3].

Aspect Details
Study Drug Cat Epithelium Extract
Purpose Allergy testing for cat allergies
Administration Method Skin prick test solution
Concentration 30 HEP/ml
Target Population Adults with allergic rhinitis/rhinoconjunctivitis symptoms
Primary Outcome Effectiveness in diagnosing cat allergies
Safety Monitoring Adverse reactions at test site

Ongoing Clinical Trials on Cat Epithelium Extract

  • Study on the Effectiveness and Safety of Allergenic Extract of Olea Europaea Pollen for Patients with Moderate-to-Severe Olive Pollen Allergy

    Not recruiting

    4 1 1
    Spain
  • Study on the Effectiveness and Safety of Phleum Pratense Pollen Extract for Patients with Moderate-to-Severe Grass Pollen Allergy

    Not recruiting

    4 1 1
    Investigated diseases:
    Germany
  • Study on the Effectiveness and Safety of Sublingual Immunotherapy with Betula Pendula Pollen Extract for Patients with Birch Pollen Allergy

    Not recruiting

    4 1 1
    Investigated diseases:
    Germany

Glossary

  • Allergic rhinitis: An allergic reaction affecting the nose, causing symptoms like sneezing, runny nose, and congestion in response to allergens like pollen or pet dander.
  • Rhinoconjunctivitis: A combination of allergic symptoms affecting both the nose (rhinitis) and eyes (conjunctivitis), often caused by airborne allergens.
  • Skin prick test: A method of allergy testing where small amounts of potential allergens are placed on the skin to see if they cause a reaction, indicating an allergy.
  • Cat Epithelium Extract: A substance derived from cat skin cells and dander, used in allergy testing to identify allergies to cats.
  • HEP: Histamine Equivalent Prick, a unit used to measure the potency of allergen extracts in skin prick tests.
  • Allergen: A substance that can cause an allergic reaction in some people, such as pollen, pet dander, or certain foods.

References

  1. http://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-sublingual-immunotherapy-with-betula-pendula-pollen-extract-for-patients-with-birch-pollen-allergy/
  2. http://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-phleum-pratense-pollen-extract-for-patients-with-moderate-to-severe-grass-pollen-allergy/
  3. http://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-allergenic-extract-of-olea-europaea-pollen-for-patients-with-moderate-to-severe-olive-pollen-allergy/