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Syros Pharmaceuticals Inc.
Sponsor

Syros Pharmaceuticals Inc.

United States 35 Cambridgepark Drive Floor 4, 02140-2325, United States

About the sponsor

Clinical research in acute myeloid leukemia focuses on RARA-positive disease subsets, including newly diagnosed and previously untreated patients. The sponsor’s studies examine targeted treatment strategies in biomarker-defined populations with an emphasis on response outcomes and hematologic remission.

  • RARA-positive AML
  • Biomarker-directed therapy
  • Complete remission

Interest extends to combination regimens involving tamibarotene with other anti-leukemic therapies, reflecting a therapeutic focus on molecularly selected AML populations.

About Specializations

Syros Pharmaceuticals Inc. runs clinical trials in conditions such as Acute myeloid leukaemia, Myelodysplastic syndrome, among others.

All trials

Ongoing trials

Clinical trials registered by this sponsor – none is enrolling right now.

Condition
Country
City
Type of trial
Recruitment status
Quick filters

3 clinical trials

Acute myeloid leukaemia

Not recruiting

Study of SY-1425 (tamibarotene) alone or with azacitidine in adult patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Syros Pharmaceuticals Inc.

Acute myeloid leukaemia

Not recruiting

Study of Tamibarotene, Venetoclax, and Azacitidine for Adults with RARA-positive Acute Myeloid Leukemia Not Eligible for Standard Therapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Syros Pharmaceuticals Inc.

Myelodysplastic syndrome

Not recruiting

Study of Tamibarotene and Azacitidine Treatment in Newly Diagnosed Adults with RARA-positive Higher-risk Myelodysplastic Syndrome (MDS)

Registered drug
Countries:AustriaAustria
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Syros Pharmaceuticals Inc.

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