Orthopaedic Surgery
Clinical research in hip arthroplasty and knee arthroplasty is central to the sponsor’s activity, with interest in perioperative care for patients undergoing joint replacement.
- Hip replacement
- Knee replacement
- Arthroplasty
The sponsor’s trial activity is directed toward patients with osteoarthritis requiring surgical treatment.
Rheumatologic Disease
Research activity includes hip and knee osteoarthritis, reflecting a focus on degenerative joint disease and its impact on surgical decision-making and patient management.
- Osteoarthritis
- Degenerative joint disease
- Joint pain
The clinical interest is concentrated on patients with advanced joint disease who are being considered for operative intervention.
Perioperative Mental Health
The sponsor also studies the interaction between surgical care and mental health treatment, particularly in patients receiving SSRIs and SNRIs before joint replacement.
- Selective serotonin reuptake inhibitors
- Serotonin-norepinephrine reuptake inhibitors
- Depression
- Anxiety
Attention is given to discontinuation syndrome and the risk of symptom recurrence during the perioperative period.
Perioperative Medication Management
Research interests extend to the temporary adjustment of psychotropic medications in the context of planned orthopaedic surgery, with emphasis on balancing surgical preparation and psychiatric stability.
- Medication discontinuation
- Psychotropic therapy
- Perioperative care
This area reflects clinical concern for safe coordination between orthopaedic treatment and ongoing management of depression and anxiety disorders.
