St. Antonius Ziekenhuis

Cardiovascular Interventional Cardiology

Clinical research at St. Antonius Ziekenhuis includes coronary artery disease, acute coronary syndrome, and stable coronary artery disease, with a strong focus on antithrombotic management around percutaneous coronary intervention and stenting.

P2Y12 inhibitor therapy
Dual antiplatelet therapy
CYP2C19 genotype-guided treatment

The sponsor also studies bleeding and ischemic balance in patients with atrial fibrillation undergoing coronary procedures.

Structural Heart Disease and Aortic Valve Care

The hospital funds research in aortic stenosis and transcatheter aortic valve implantation, with attention to peri-procedural bleeding prevention and post-procedure antithrombotic strategy.

TAVI
Protamine administration
CT-guided antithrombotic therapy

This area reflects a clear interest in optimizing care for patients with severe aortic valve stenosis.

Pulmonary Vascular Disease

Research activity extends to chronic thromboembolic pulmonary hypertension and chronic thromboembolic disease, including treatment support around balloon pulmonary angioplasty and anticoagulant selection.

CTEPH
CTED
Direct oral anticoagulants and vitamin K antagonists

The sponsor’s interest in this field also covers procedural safety, including bleeding and lung injury outcomes.

Pulmonary Fibrosis and Molecular Imaging

St. Antonius Ziekenhuis supports studies in progressive pulmonary fibrosis using PET/CT imaging with FAPI to distinguish inflammatory and fibrotic disease patterns.

Fibrosis phenotyping
Inflammation imaging
Fibroblast activation protein tracers

This research area links respiratory medicine with advanced diagnostic imaging.

Perioperative Pain and Breast Cancer Surgery

The sponsor also investigates pain control after mastectomy, with interest in regional anesthesia approaches such as the PECS II block for postoperative pain.