Cardiovascular Interventional Cardiology
Clinical research at St. Antonius Ziekenhuis includes coronary artery disease, acute coronary syndrome, and stable coronary artery disease, with a strong focus on antithrombotic management around percutaneous coronary intervention and stenting.
- P2Y12 inhibitor therapy
- Dual antiplatelet therapy
- CYP2C19 genotype-guided treatment
The sponsor also studies bleeding and ischemic balance in patients with atrial fibrillation undergoing coronary procedures.
Structural Heart Disease and Aortic Valve Care
The hospital funds research in aortic stenosis and transcatheter aortic valve implantation, with attention to peri-procedural bleeding prevention and post-procedure antithrombotic strategy.
- TAVI
- Protamine administration
- CT-guided antithrombotic therapy
This area reflects a clear interest in optimizing care for patients with severe aortic valve stenosis.
Pulmonary Vascular Disease
Research activity extends to chronic thromboembolic pulmonary hypertension and chronic thromboembolic disease, including treatment support around balloon pulmonary angioplasty and anticoagulant selection.
- CTEPH
- CTED
- Direct oral anticoagulants and vitamin K antagonists
The sponsor’s interest in this field also covers procedural safety, including bleeding and lung injury outcomes.
Pulmonary Fibrosis and Molecular Imaging
St. Antonius Ziekenhuis supports studies in progressive pulmonary fibrosis using PET/CT imaging with FAPI to distinguish inflammatory and fibrotic disease patterns.
- Fibrosis phenotyping
- Inflammation imaging
- Fibroblast activation protein tracers
This research area links respiratory medicine with advanced diagnostic imaging.
Perioperative Pain and Breast Cancer Surgery
The sponsor also investigates pain control after mastectomy, with interest in regional anesthesia approaches such as the PECS II block for postoperative pain.
- Breast surgery analgesia
- Regional nerve block
- Perioperative pain management
These studies focus on improving comfort and recovery in patients undergoing breast cancer surgery.
