Karolinska Institutet

Cardiovascular and Renal Medicine

Clinical research includes heart failure with reduced ejection fraction, severe chronic kidney disease, acute myocardial infarction, and left ventricular thrombosis, with additional interest in treatment strategies for acute ischaemic stroke.

  • Heart failure
  • Chronic kidney disease
  • Myocardial infarction
  • Stroke
  • Thromboembolic disease

Work in this area also extends to anticoagulation, biomarker-informed treatment selection, and cardiovascular complications after major cardiac events.

Oncology and Haematology

The sponsor supports studies in breast cancer, colorectal cancer, prostate cancer, multiple myeloma, acute myeloid leukaemia, and glioblastoma, together with hereditary cancer risk in Lynch syndrome.

  • Breast malignancies
  • Colorectal neoplasia
  • Prostate cancer
  • Blood cancers
  • Brain tumours

Research interests include treatment optimisation, maintenance approaches, recurrence prevention, and precision-medicine strategies linked to tumour biology.

Immunology, Allergy, and Infectious Disease

Trials address allergic rhinitis, dog allergy, grass pollen allergy, rheumatoid arthritis, RSV infection, and Crimean-Congo haemorrhagic fever, reflecting a broad focus on immune-mediated and infectious conditions.

  • Allergic disease
  • Autoimmune inflammation
  • Respiratory viral infection
  • Viral haemorrhagic fever
  • Allergen-specific immunotherapy

Additional areas include immune modulation, vaccine-related responses, and symptom control in chronic inflammatory disease.

Neurology, Psychiatry, and Cognitive Health

Research activity covers Alzheimer’s disease, major depressive disorder, alcohol use disorder, and neurorehabilitation after stroke, alongside studies in pain-related neuromuscular conditions.

  • Neurodegenerative disease
  • Depression
  • Addiction medicine
  • Brain injury recovery
  • Temporomandibular disorders

There is also interest in cognitive function, behavioural outcomes, and treatment-related neurological effects.

Women’s Health, Reproductive Medicine, and Musculoskeletal Disorders

Clinical studies include polycystic ovary syndrome, ectopic pregnancy, post-abortion contraception, sexual function after cancer treatment, and skeletal conditions such as osteogenesis imperfecta.

  • Reproductive health
  • Contraception
  • Sexual medicine
  • Bone fragility disorders
  • Dental bone regeneration

Related research also includes fertility-adjacent care, hormonal treatment effects, and supportive procedures in oral surgery.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Mifepristone and Letrozole for Treating Ectopic Pregnancy in Comparison to Methotrexate

    Recruiting

    2 1 1 1
    Denmark Finland Latvia Sweden
  • Ropivacaine hydrochloride versus electrolytes for pain relief in women undergoing second‑trimester medical abortion after 13 weeks

    Not yet recruiting

    3 1 1
    Sweden
  • Study of RSVPreF3 vaccine with AS01E adjuvant in adults aged 60-65 and over 80 years to prevent respiratory syncytial virus infection

    Not yet recruiting

    3 1 1 1
    Investigated Diseases:
    Sweden
  • Study of eplerenone in patients with heart failure and reduced ejection fraction who also have severe chronic kidney disease

    Not yet recruiting

    2 1 1 1
    Investigated Diseases:
    Sweden
  • Study on Thiopental Sodium Dose During Electroconvulsive Therapy for Patients with Major Depressive Disorder

    Not yet recruiting

    3 1 1 1
    Investigated Drugs:
    Sweden
  • Evaluation of Alutard SQ dog allergen immunotherapy in patients with allergic rhinitis due to dog allergy – A one-year study in Swedish practice

    Not yet recruiting

    3 1 1 1
    Sweden