Transplantation and post-transplant care
Research activity includes heart transplantation, kidney transplantation, and simultaneous pancreas-kidney transplantation, with attention to cardiac allograft vasculopathy, immunosuppression, and incisional hernia risk in transplant recipients.
- Cardiac allograft vasculopathy
- Simultaneous pancreas-kidney transplantation
- Immunosuppressive therapy
- Liver transplant candidates
Interest also extends to lipid management and metabolic complications after transplantation.
Type 1 diabetes and beta-cell preservation
Clinical research focuses on newly diagnosed type 1 diabetes in children, adolescents, and adults, with emphasis on preserving residual beta-cell function and evaluating immune-based treatment strategies.
- Recent-onset type 1 diabetes
- Residual beta-cell function
- Immune modulation
- Pediatric and young adult diabetes
The sponsor also studies end-stage kidney disease in people with type 1 diabetes.
Peripheral arterial disease and diabetic limb ischemia
Trials address chronic limb-threatening ischemia, lower limb ischemia, diabetic foot syndrome, and diabetic foot ulcers, with a strong focus on limb salvage and wound-related outcomes.
- Chronic limb-threatening ischemia
- Diabetic foot ulcers
- Percutaneous transluminal angioplasty
- Major amputation
Research also includes autologous cell therapy combined with vascular intervention in severe ischemic disease.
Regenerative cell therapy and vascular repair
The sponsor investigates autologous bone marrow-derived mononuclear cell therapy and related approaches for patients with advanced ischemic disease, comparing tissue oxygenation, wound healing, and clinical recovery in diabetic limb ischemia.
- Autologous cell therapy
- Tissue oxygenation
- Wound healing
- Peripheral vascular disease
These studies link regenerative medicine with vascular surgery and diabetic foot care.
Metabolic disease and obesity
Research includes pharmacological obesity treatment in liver transplant candidates, reflecting interest in metabolic risk, body weight management, and transplant-related comorbidity.
- Obesity
- Metabolic disease
- Liver transplantation
- Cardiometabolic risk
Attention is also given to lipid disorders in the setting of transplantation and chronic disease.
