Breast and Ovarian Oncology
Breast cancer research includes triple-negative breast cancer and the management of disease-related complications such as brain metastases. The sponsor also supports work on fertility preservation before systemic treatment, including ovarian stimulation and cryopreservation strategies.
- Triple-negative breast cancer
- Brain metastases in breast cancer
- Fertility preservation before chemotherapy
These activities reflect interest in both disease control and treatment-related quality-of-life issues in women with cancer.
Central Nervous System Metastatic Disease
Clinical research spans brain metastases from non-small cell lung cancer, breast cancer, and melanoma, as well as brain radionecrosis after radiotherapy. Imaging-focused studies explore metabolic and molecular detection of intracranial lesions.
- Brain radionecrosis
- Newly diagnosed brain metastases
- Advanced PET imaging for intracranial disease
The sponsor is active in defining better diagnostic and therapeutic options for metastatic involvement of the brain.
Urologic and Prostate Cancer
Research activity includes metastatic prostate cancer, oligometastatic hormone-sensitive prostate cancer, and recurrence in the previously irradiated prostate bed. The portfolio also covers non-muscle-invasive bladder cancer that remains refractory to standard treatment.
- Metastatic prostate cancer
- Oligometastatic hormone-sensitive prostate cancer
- Refractory non-muscle-invasive bladder cancer
These studies focus on advanced local and metastatic urologic malignancies, with attention to both salvage treatment and disease control.
Digestive and Peritoneal Malignancies
The sponsor supports trials in rectal adenocarcinoma, gastric and gastro-oesophageal junction adenocarcinomas, and advanced peritoneal metastasis from colon cancer and the colorectal junction. Research also addresses small cell lung carcinoma in the context of metastatic detection.
- Rectal adenocarcinoma
- Gastric and gastro-oesophageal junction adenocarcinoma
- Peritoneal metastases from colorectal cancer
These areas highlight interest in locally advanced and disseminated gastrointestinal cancers requiring multimodal care.
Metastatic Bone Disease and Treatment Toxicity
Additional research targets vertebral bone metastases requiring stereotactic radiotherapy and symptom management in chemotherapy-induced peripheral neuropathy. The sponsor also studies supportive approaches for patients with metastatic disease burden.
- Inoperable vertebral bone metastases
- Chemotherapy-induced peripheral neuropathy
- Supportive care in metastatic cancer
These topics show sustained attention to complications of cancer treatment and metastatic spread to the skeleton.
