Allergic Rhinitis and Rhinoconjunctivitis
Clinical research focuses on moderate-to-severe intermittent and persistent allergic rhinitis and rhinoconjunctivitis, including cases associated with controlled mild-to-moderate allergic asthma. The portfolio includes both seasonal and perennial disease patterns.
- Grass pollen and cupressaceae allergy
- Birch pollen-induced respiratory allergy
- House dust mite-associated disease
Research activity also covers symptom control during pollen seasons and the clinical burden linked to allergen exposure in adolescents and adults.
Allergen Immunotherapy
The sponsor funds studies in specific immunotherapy for respiratory allergy, with interest in subcutaneous immunotherapy and sublingual immunotherapy approaches. The work centers on allergen-directed treatment for patients sensitized to inhalant allergens.
- Polymerized allergen extracts
- Mannan-conjugated allergoids
- Dust mite and mixed pollen immunotherapy
Key therapeutic areas include treatment of sensitization to Dermatophagoides pteronyssinus, Dermatophagoides farinae, and related aeroallergens.
Aeroallergen Characterisation
Part of the research portfolio is devoted to the assessment of allergenic extracts and their biological activity, with a focus on defining potency for clinically relevant airborne allergens.
- Blomia tropicalis
- Lepidoglyphus destructor
- Phleum pratense and Dactylis glomerata
Additional interest extends to Quercus ilex, Quercus robur, and birch pollen, reflecting a broad focus on environmental allergens relevant to respiratory disease.
Recurrent Urinary Tract Infections
The sponsor also supports clinical research in recurrent non-complicated urinary tract infections, with attention to prevention of repeated infectious episodes in women with localized recurrent cystitis.
- Mucosal bacterial immunotherapy
- Recurrent cystitis
- Infection recurrence reduction
This area broadens the therapeutic scope beyond allergy into urogenital infectious disease.
