Fundacion Para La Investigacion Biomedica Del Hospital Universitario La Princesa

Pharmacogenetics and personalized prescribing

The sponsor supports clinical research in pharmacogenetics aimed at tailoring treatment to individual genetic profiles, with a strong focus on improving medication selection and reducing adverse reactions in routine care.

  • CYP2D6 genotyping
  • SLCO1B1, ABCG2, and CYP2C9 variants
  • Statin-associated musculoskeletal adverse reactions
  • Acute postoperative pain treatment

Its research activity also includes medication-response studies in women’s health, reflecting interest in gene-informed treatment across multiple therapeutic settings.

Neurology and immune-mediated epilepsy

Clinical work in neurology centers on severe refractory epilepsies, including Rasmussen encephalitis and other immune-mediated seizure disorders that require advanced therapeutic approaches.

  • Autoimmune refractory epilepsy
  • Rasmussen encephalitis
  • Mesenchymal stem cell therapy
  • Children and adolescents with refractory seizures

These studies place emphasis on difficult-to-treat epileptic conditions in paediatric and adolescent populations.

Cardiovascular medicine and perioperative care

The sponsor is involved in cardiovascular research spanning prevention, surgical recovery, and haemodynamic function, with attention to both chronic risk management and immediate postoperative physiology.

  • Primary and secondary prevention of cardiovascular risk
  • Statin treatment safety
  • Immediate cardiac surgery post-operative period
  • Right ventricular function and pulmonary vascular mechanics

Research topics also include the use of inhaled nitric oxide in postoperative cardiac patients.

Gastroenterology and inflammatory disease

In gastroenterology, the sponsor studies treatment effects in ulcerative colitis, with a focus on inflammatory disease management and related vascular or coagulation outcomes.

  • Ulcerative colitis
  • Tofacitinib
  • Platelet function
  • Coagulation

This area connects intestinal inflammation with broader haematological and thrombotic considerations.

Healthy volunteers and therapeutic technique evaluation

The sponsor also includes studies in healthy volunteers and research on therapeutic techniques for symptom control, supporting evaluation of treatment effects in controlled clinical settings.

  • Healthy volunteers
  • Therapeutic techniques for acute postoperative pain
  • Personalized treatment approaches
  • Medication safety and tolerability

These topics align with its broader interest in individualized care across pain management, perioperative medicine, and precision therapeutics.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on the Safety of Repeated Intra-Arterial Infusion of Mesenchymal Stem Cells for Children and Adolescents with Refractory Epilepsy

    Recruiting

    1 1 1
    Investigated diseases:
    Spain
  • Study on the Effect of Genetic Testing and Training on Muscle Side Effects in Patients Taking Statins for Cardiovascular Risk Prevention

    Recruiting

    3 1 1 1
    Spain
  • Study on Improving Pain Relief After Surgery Using Tramadol and Dexketoprofen Based on Genetic Testing for Patients with Acute Postoperative Pain

    Recruiting

    3 1 1 1
    Investigated diseases:
    Spain
  • Study on the Effects of Inhaled Nitric Oxide on Heart and Lung Function After Cardiac Surgery

    Not yet recruiting

    3 1 1 1
    Investigated drugs:
    Spain
  • Study on the Effects of Tofacitinib and Drug Combination on Blood Clotting in Patients with Ulcerative Colitis

    Not recruiting

    3 1 1 1
    Investigated diseases:
    Spain