Oncology and Tumour-Directed Therapy
Oncology research spans solid and haematological malignancies, with strong activity in pancreatic cancer, colorectal cancer, gastro-oesophageal cancer, cholangiocarcinoma, urothelial cancer, prostate cancer, breast cancer, melanoma, glioblastoma, and paediatric leukaemia.
- Peritoneal metastases
- Targeted therapy and immunotherapy
- Image-guided surgery and PET imaging
- Radiotherapy combinations
- Paediatric and adult cancer care
Work in this area also includes neuroendocrine tumours, sarcomas, head and neck cancer, and carcinoma of unknown primary.
Neurology, Pain, and Neuroimmunology
Clinical research covers migraine, anti-NMDAR encephalitis, neuromyelitis optica spectrum disorder, autism spectrum disorder, and complex regional pain syndrome, alongside studies in glioma and other central nervous system disorders.
- Headache and trigeminovascular biology
- Autoimmune encephalitis
- Neuropathic pain
- Neuro-oncology
- Neurodevelopmental disorders
Additional interest extends to epilepsy-related and inflammatory neurological conditions.
Cardiovascular, Renal, and Metabolic Medicine
Research includes atherosclerosis, cardiogenic shock, aortic stenosis, coronary artery disease, cardiac sarcoidosis, and high cardiovascular risk populations, as well as kidney transplantation and autosomal dominant polycystic kidney disease.
- Transcatheter valve care
- Antithrombotic treatment selection
- Tacrolimus optimisation
- Lipid-lowering therapy
- Renal physiology and hemodialysis
Metabolic interests also include obesity, statin intolerance, and muscle protein turnover.
Autoimmune, Inflammatory, and Infectious Diseases
Investigations address rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, pulmonary sarcoidosis, Graves’ orbitopathy, chronic hepatitis B, and HIV-1, with broader activity in immune-mediated and inflammatory disorders.
- Biologic and immunomodulatory treatment
- Inflammatory bowel disease
- Endocrine autoimmunity
- Vaccine response
- Viral latency research
Work also includes sepsis and other critical care infection-related conditions.
Paediatrics, Surgery, and Perioperative Care
Clinical studies involve paediatric oncology, congenital gastrointestinal disorders, orthopaedic developmental conditions, esophageal atresia, postoperative pancreatic fistulas, and perioperative coagulation management.
- Paediatric transplant and drug monitoring
- Fluorescence-guided surgery
- Hepatic arterial infusion and intraperitoneal therapy
- Orthopaedic and musculoskeletal disorders
- Perioperative blood management
Research further covers quality of life, exercise capacity, and supportive care in surgical and chronic disease settings.
