Critical Care and Cardiovascular Medicine
CHRU De Nancy supports clinical research in septic shock, cardiogenic shock, and out-of-hospital cardiac arrest, with attention to acute organ support, hemodynamic stability, and neurological outcome. Its trial portfolio also includes advanced therapy for severe circulatory failure and short-term intensive care management.
- Septic shock
- Cardiogenic shock
- Out-of-hospital cardiac arrest
- Levosimendan and inotropic support
Research in this area also extends to heart failure outcomes and the management of major acute cardiovascular complications.
Neurology, Neuro-oncology, and Stroke
The sponsor is active in research on acute ischemic stroke, including reperfusion-related treatment strategies, as well as imaging and therapeutic approaches for low-grade glioma, meningioma, and adult medulloblastoma. The portfolio reflects interest in both emergency neurological care and tumor characterization.
- Ischemic stroke
- Low-grade glioma
- Meningioma
- Adult medulloblastoma
Diagnostic work in this field includes PET imaging and cerebral reperfusion assessment.
Transplantation, Renal Medicine, and Donor Care
Clinical studies at CHRU De Nancy focus on kidney transplantation, end-stage renal disease, and post-transplant renal and cardiovascular complications. The sponsor also investigates care in brain-dead organ donors and the hemodynamic conditions relevant to organ procurement.
- Kidney transplantation
- End-stage renal disease
- Brain-dead organ donors
- Calcineurin inhibitor-associated complications
Additional interest includes graft function, vascular changes after transplantation, and donor physiology in the setting of organ harvesting.
Hepatology, Gastroenterology, and Metabolic Liver Disease
The sponsor funds research in cirrhosis, non-alcoholic fatty liver disease, and short bowel syndrome, with emphasis on liver-related imaging, immune response to vaccination in chronic liver disease, and treatment-related absorption issues in gastrointestinal disorders.
- Cirrhosis
- Non-alcoholic hepatic steatosis
- Short bowel syndrome
- Hepatic fibrosis
Its studies also address liver tissue characterization and clinical management in advanced chronic liver conditions.
Maternal-Fetal, Pediatric, and Surgical Care
CHRU De Nancy is involved in research on fetal growth restriction, adnexal torsion, perioperative anxiety, and pediatric neurogenic bladder linked to spina bifida. The sponsor also studies transplant-related immune complications such as acute graft-versus-host disease.
- Fetal growth restriction
- Adnexal torsion
- Spina bifida
- Acute graft-versus-host disease
These studies span diagnostic evaluation, perioperative management, and specialized pediatric and transplant-related care.
