Rheumatology and Autoimmune Disease
Rheumatoid arthritis research includes treatment strategies for persistent inflammatory disease, with interest in biologic sequencing and disease control. Systemic sclerosis is also a focus, including severe, treatment-resistant forms associated with skin fibrosis and immune-mediated tissue damage.
- Rheumatoid arthritis
- Systemic sclerosis
- Autoimmune disease
Work in this area reflects a strong interest in immune modulation, refractory disease, and outcomes linked to inflammatory activity.
Hepatology and Liver Cancer
Hepatocellular carcinoma and intrahepatic cholangiocarcinoma are central areas of clinical investigation, alongside treatment-related liver injury such as cholestatic hepatitis induced by immune checkpoint inhibitors. Research also extends to liver-directed oncology and disease control in advanced hepatic carcinoma.
- Hepatocellular carcinoma
- Intrahepatic cholangiocarcinoma
- Immune-related cholestatic hepatitis
These studies place emphasis on liver malignancies, immune toxicity affecting the liver, and locoregional cancer management.
Neurology, Sleep, and Neurodevelopment
Clinical research includes multiple sclerosis, Alzheimer disease, idiopathic hypersomnia, and insomnia disorder, with additional interest in neurodevelopmental disorders linked to CTNNB1 variants. The portfolio also addresses motor function and sleep-related symptoms in neurologic and cognitive conditions.
- Multiple sclerosis
- Alzheimer disease
- Sleep disorders
This area spans chronic neurologic disease, cognitive impairment, and developmental conditions affecting movement and sleep.
Respiratory and Pediatric Infectious Disease
Chronic obstructive pulmonary disease and severe asthma are key respiratory themes, with attention to airway inflammation, mucus-related disease burden, and exacerbation prevention. Pediatric research includes community-acquired alveolar pneumonia and perioperative care in children.
- Chronic obstructive pulmonary disease
- Severe asthma
- Community-acquired pneumonia in children
Additional work involves airway disease control and pediatric treatment pathways across respiratory and hospital-based settings.
Pain, Anesthesia, and Renal Metabolism
Research covers acute low back pain, general anesthesia, locoregional anesthesia, and sedation approaches in pediatric surgery. The sponsor also studies transient hypercalciuria, chronic renal failure, and renal protection in patients with kidney-related disease.
- Acute pain management
- Pediatric anesthesia
- Renal and metabolic disorders
These topics reflect interest in perioperative care, symptom relief, and metabolic consequences affecting kidney health.
