Centre Hospitalier Universitaire D’Angers

Hematology and Blood Cancers

Clinical research includes acute myeloid leukemia, chronic lymphocytic leukemia, follicular lymphoma, Hodgkin lymphoma, and myeloma, with attention to treatment strategies, survival outcomes, and supportive care in hematologic malignancies.

  • Acute myeloid leukemia
  • Chronic lymphocytic leukemia
  • Follicular lymphoma
  • Hodgkin lymphoma
  • Myeloma

Research activity also extends to allogeneic transplantation and graft-versus-host disease prevention in patients with high-risk blood disorders.

Solid Tumors and Gastrointestinal Oncology

The sponsor supports studies in cholangiocarcinoma, hepatocellular carcinoma, gastric cardia cancer, esophageal squamous cell carcinoma, non-small cell lung carcinoma, small cell lung carcinoma, pleural mesothelioma, melanoma, and deficient mismatch repair colorectal cancer.

  • Cholangiocarcinoma
  • Hepatocellular carcinoma
  • Gastric cardia cancer
  • Esophageal squamous cell carcinoma
  • Melanoma

Its oncology portfolio also includes locally advanced cutaneous squamous cell carcinoma and other advanced solid tumors requiring specialized cancer care.

Neuro-ophthalmology and Rare Mitochondrial Disorders

Research is active in inherited optic neuropathies such as dominant optic atrophy and Leber’s hereditary optic neuropathy, alongside broader interest in visual pathway disorders linked to mitochondrial disease.

  • Dominant optic atrophy
  • Leber’s hereditary optic neuropathy
  • OPA1-related disease
  • Mitochondrial optic neuropathy

These studies focus on preserving visual function and assessing tolerability in rare neuro-ophthalmic conditions.

Neurology and Critical Care

The trial portfolio includes aneurysmal subarachnoid hemorrhage with vasospasm, reflecting interest in acute neurological injury and intensive care management.

  • Aneurysmal subarachnoid hemorrhage
  • Vasospasm
  • Neurological outcome
  • Critical care neurology

Research in this area addresses recovery after severe cerebrovascular events and related complications.

Orthopaedics, Allergy, and Pediatric Endocrinology

Additional studies cover lower limb trauma requiring immobilisation and prevention of venous thromboembolism, as well as biotherapy hypersensitivity testing in allergology.

  • Lower limb trauma
  • Venous thromboembolism prevention
  • Biotherapy allergy testing
  • Hypothalamic obesity
  • Craniopharyngioma

Paediatric work also includes hypothalamic obesity secondary to craniopharyngioma, linking endocrine care with long-term metabolic management.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Safe Skin Test Concentrations for Biotherapy Allergies in Patients with Cancer Using Atezolizumab, Daratumumab, and Nivolumab

    Recruiting

    3 1 1 1
    France
  • Study Comparing Rivaroxaban and Drug Combination for Preventing Blood Clots in Patients with Lower Limb Injuries Requiring Immobilization

    Recruiting

    3 1 1 1
    France
  • A study to evaluate the effectiveness of semaglutide for treating obesity caused by craniopharyngioma in children aged 12 to 17 years.

    Not yet recruiting

    3 1 1
    Investigated diseases:
    Investigated drugs:
    France
  • A study to evaluate the effectiveness of nicotinamide in patients with Leber’s hereditary optic neuropathy who have experienced vision loss within the last 18 months

    Not yet recruiting

    2 1 1 1
    Investigated diseases:
    Investigated drugs:
    France
  • Study on Milrinone Infusion for Treating Vasospasm in Patients with Aneurysmal Subarachnoid Hemorrhage

    Not recruiting

    3 1 1 1
    Investigated diseases:
    Investigated drugs:
    France
  • Study on the Safety and Effects of Nicotinamide for Patients with Dominant Optic Atrophy

    Not recruiting

    3 1 1 1
    Investigated diseases:
    Investigated drugs:
    France