Cara Therapeutics Inc.

Dermatology and Pruritus

Clinical research is focused on moderate-to-severe itch in adults with notalgia paresthetica, with attention to symptom control and patient discomfort linked to chronic skin-related sensory disturbance.

  • Itch intensity
  • Chronic pruritus
  • Notalgia paresthetica

The sponsor’s current activity centers on therapeutic options for persistent pruritic symptoms in an adult dermatologic population.

Neuropathic Sensory Symptoms

Research interest extends to the sensory manifestations of notalgia paresthetica, particularly the overlap between localized itching and neuropathic discomfort.

  • Sensory disturbance
  • Localized neuropathic itch
  • Adult symptom burden

This area reflects a therapeutic focus on conditions where itch is driven by altered nerve-related signaling rather than purely inflammatory skin disease.

Oral Therapeutics

The clinical program includes interest in oral treatment options for managing persistent itch, with evaluation centered on patient-reported relief and tolerability in an outpatient setting.

  • Systemic anti-itch therapy
  • Patient-reported outcomes
  • Symptom relief

Development activity is directed toward a pharmaceutical approach for a chronic condition with limited established therapeutic choices.

Adult Ambulatory Care

Trials are positioned within an adult outpatient population, supporting research into day-to-day management of persistent itch associated with a chronic sensory disorder.

  • Adult patients
  • Outpatient management
  • Chronic symptom control

The sponsor’s research landscape is concentrated on improving treatment options for adults living with ongoing pruritic symptoms.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on the Effectiveness and Safety of Difelikefalin for Adults with Moderate-to-Severe Itching from Notalgia Paresthetica

    Not recruiting

    1 1
    Investigated diseases:
    Investigated drugs:
    Germany Poland Spain