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Ziekenhuis Amstelland

Research site

The Netherlands Laan Van De Helende Meesters 8, 1186 AM Amstelveen, The Netherlands

  • 8 trials recruiting
  • Atrial fibrillation · Arteriosclerosis · Chronic lymphocytic leukaemia
  • Adult patients

About Specializations

Ziekenhuis Amstelland in Amstelveen, The Netherlands specialises in clinical trials of conditions such as Atrial fibrillation, Arteriosclerosis, Chronic lymphocytic leukaemia, Hormone receptor positive HER2 negative breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases at Ziekenhuis Amstelland

Research at this hospital in Cardiology focuses on cardiovascular diseases, especially atherosclerotic cardiovascular disease, atrial fibrillation, and broader outcomes linked to heart and vascular risk. The trials are designed to test new treatment strategies, improve prevention, and evaluate whether therapies can reduce major events such as heart attack, stroke, and cardiovascular death.

  • ASCVD prevention and reduction of major cardiovascular events
  • Atrial fibrillation and stroke prevention after acute stress-related episodes
  • Cardiovascular risk reduction in people with type 2 diabetes or overweight

Several studies also examine whether newer medicines can improve long-term heart and vascular outcomes when added to standard care.

Neoplasms and Cancer Treatment Research

The site is active in oncology research across several neoplasms, including breast cancer, metastatic colorectal cancer, and diffuse large B-cell lymphoma. These trials aim to refine treatment choices, explore treatment de-escalation where appropriate, and assess whether targeted or immune-based approaches can improve outcomes for people with difficult-to-treat cancers.

  • Breast cancer, including triple negative breast cancer and HR-positive, HER2-negative disease
  • Metastatic colorectal cancer and treatment intensity optimization
  • Diffuse large B-cell lymphoma and prevention of treatment-related heart problems

This research combines efforts to improve cancer control while also considering safety, quality of life, and the balance between treatment benefit and burden.

Female Urogenital Diseases and Pregnancy Complications

Clinical studies in this area include research on infertility and reproductive health, with the goal of improving diagnostic and treatment pathways for women trying to conceive. The work also reflects interest in practical interventions that may support better fertility-related care in everyday clinical settings.

  • Infertility and evaluation of fertility-related procedures
  • Research aimed at improving the chances of conception leading to live birth
  • Comparing approaches that may help guide reproductive care more effectively

At Ziekenhuis Amstelland, this field adds a reproductive health dimension to a portfolio that is otherwise strongly centered on cardiovascular and cancer research.

Hemic and Lymphatic Diseases

The hematology research portfolio includes studies in multiple myeloma and diffuse large B-cell lymphoma. These trials are focused on improving disease control, exploring treatment sequencing, and reducing complications from therapy, especially when patients need effective treatment over a longer period.

  • Multiple myeloma and strategies for treatment-free intervals
  • DLBCL and prevention of heart damage linked to cancer therapy
  • Evaluating whether treatment approaches can preserve effectiveness while limiting toxicity

This area shows a clear interest in balancing cancer treatment benefit with safety, particularly in patients who may already face elevated cardiovascular risk.

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Site location
Laan Van De Helende Meesters 81186 AM AmstelveenThe Netherlands
Recruiting now
8 trials
Conditions studied
24

More sites in AmstelveenThe Netherlands

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
Recruitment status
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20 clinical trials

Phase 3 Study of Etripamil Nasal Spray Compared with Placebo in Patients with Atrial Fibrillation and Rapid Ventricular Rate

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Etripamil
  • Sponsor:Milestone Pharmaceuticals Inc.

Effect of elecoglipron plus dapagliflozin on cardiovascular outcomes in adults with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF)

Registered drug
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

Rituximab and venetoclax treatment for 6 vs 26 cycles in patients with relapsed or refractory chronic lymphocytic leukemia

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Venetoclax
  • Sponsor:Haemato Oncology Foundation For Adults Netherlands

Study of pembrolizumab, capecitabine, or olaparib in patients with early-stage triple negative breast cancer and remaining disease after initial treatment

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

Study on Apixaban and Edoxaban for Preventing Stroke in Patients with Recent Perioperative Atrial Fibrillation After Noncardiac Surgery

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Apixaban
  • Sponsor:Hamilton Health Sciences Corporation

Study on Treatment-Free Intervals for Newly Diagnosed Multiple Myeloma Patients Using Daratumumab, Lenalidomide, and Dexamethasone

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Daratumumab
  • Sponsor:Haemato Oncology Foundation For Adults Netherlands

Study on Preventing Heart Problems in Patients with Diffuse Large B-Cell Lymphoma Using Dexrazoxane and a Drug Combination

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Cyclophosphamide
  • Sponsor:Haemato Oncology Foundation For Adults Netherlands

Dose-Reduced Oxaliplatin and Drug Combination Study for Older Patients with Metastatic Colorectal Cancer

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:65+ years
  • Substances:Capecitabine
  • Sponsor:Leids Universitair Medisch Centrum (LUMC)

Atrial fibrillation

Not yet recruiting

Prevention of Stroke and Systemic Embolism in Atrial Fibrillation Patients Treated with REGN7508 (cenvacibart) versus Apixaban

Registered drug
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Apixaban
  • Sponsor:Regeneron Pharmaceuticals Inc.

Chronic lymphocytic leukaemia+1

Not yet recruiting

Study of Ibrutinib Plus Ritonavir in Adults with Chronic Lymphocytic Leukemia, Lymphoplasmacytic Lymphoma, and Mantle Cell Lymphoma

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Ibrutinib
  • Sponsor:Haemato Oncology Foundation For Adults Netherlands

Evaluation of Tirzepatide Versus Dulaglutide on Major Adverse Cardiovascular Events in Type 2 Diabetes Patients with High Cardiovascular Risk

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Dulaglutide
  • Sponsor:Eli Lilly & Co.

Arteriosclerosis

Not recruiting

Study of maridebart cafraglutide to reduce cardiovascular problems in overweight or obese patients with atherosclerotic cardiovascular disease

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.
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