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ze:ro Praxen MVZ fuer Nierenerkrankungen und Bluthochdruck GmbH Mannheim

Verified siteinfo

Germany Georg-Lechleiter-Platz 3, Schwetzingerstadt, 68165 Mannheim, Germany

  • 6 trials recruiting
  • Arteriosclerosis · Cardiac failure · Aortic valve stenosis
  • Adult patients

About Specializations

ze:ro Praxen MVZ fuer Nierenerkrankungen und Bluthochdruck GmbH Mannheim in Mannheim, Germany specialises in clinical trials of conditions such as Arteriosclerosis, Cardiac failure, Aortic valve stenosis, Atrial fibrillation, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

At ze:ro Praxen MVZ fuer Nierenerkrankungen und Bluthochdruck GmbH Mannheim, clinical research is centered on cardiovascular diseases, with studies focused on common and high-risk conditions such as atherosclerotic cardiovascular disease, elevated lipoprotein(a), and heart failure. The trials are mainly designed to test new treatment options and to better understand how to reduce serious heart and vessel complications.

  • Research on lowering lipoprotein(a) to slow the progression of calcific aortic valve stenosis
  • Studies aimed at reducing major cardiovascular events in people with established cardiovascular disease
  • Trials evaluating approaches for heart failure, including people with preserved or mildly reduced ejection fraction and obesity
  • Research in type 2 diabetes, hypertension, and cardiovascular risk to improve prevention of heart-related complications

Overall, the site is contributing to research that seeks to improve treatment effectiveness, lower the risk of myocardial infarction and stroke, and support better long-term care for patients with complex cardiometabolic conditions.

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Site location
Georg-Lechleiter-Platz 3, Schwetzingerstadt68165 MannheimGermany
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Recruiting now
6 trials
Conditions studied
10
Partner status
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Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
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12 clinical trials

Cardiac failure

Recruiting

Study of maridebart cafraglutide for patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

Cardiovascular disorder+2

Recruiting

Study of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:BI 690517
  • Sponsor:Boehringer Ingelheim Espana S.A.

Arteriosclerosis

Recruiting

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Laroprovstat
  • Sponsor:AstraZeneca AB

Study on Baxdrostat and Dapagliflozin for Preventing Heart Failure in Patients at High Risk

Recruiting
Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:AstraZeneca AB

Coronary artery disease+2

Recruiting

Study of YMI024 to Reduce Inflammation in Adults with Stable Coronary Artery Disease and Elevated hsCRP

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Novartis Pharma AG

Aortic valve stenosis

Recruiting

Study on Pelacarsen for Slowing Calcific Aortic Valve Stenosis in Patients

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Pelacarsen
  • Sponsor:Novartis Pharma AG

Cardiac failure

Not recruiting

A study comparing ziltivekimab to placebo in patients with heart failure with mildly reduced or preserved ejection fraction and inflammation

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Ziltivekimab
  • Sponsor:Novo Nordisk A/S

Arteriosclerosis

Not recruiting

Study on the Effects of Pelacarsen on Heart Disease in Patients with Cardiovascular Conditions

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Pelacarsen
  • Sponsor:Novartis Pharma AG

Atrial fibrillation

Not recruiting

Study on Milvexian and Apixaban for Preventing Stroke in Patients with Atrial Fibrillation

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Andexanet Alfa
  • Sponsor:Janssen Cilag International

Arteriosclerosis

Not recruiting

Long-term safety study of pelacarsen in patients with atherosclerotic cardiovascular disease who completed the Lp(a)HORIZON trial

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Pelacarsen
  • Sponsor:Novartis Pharma AG

Arteriosclerosis

Not recruiting

Study of pelacarsen and inclisiran in patients with atherosclerotic cardiovascular disease who have high levels of LDL cholesterol and lipoprotein(a)

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Inclisiran
  • Sponsor:Novartis Pharma AG

Type IIa hyperlipidaemia

Not recruiting

Study on the Effectiveness of Enlicitide Chloride in Reducing Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Merck Sharp & Dohme LLC
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