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Zachodniopomorskie Centrum Onkologii

Research site

Poland Ul. Strzalowska 22, 71-730 Szczecin, Poland

  • 6 trials recruiting
  • Hormone receptor positive HER2 negative breast cancer · Breast cancer · Malignant melanoma
  • Adults and children

About Specializations

Zachodniopomorskie Centrum Onkologii in Szczecin, Poland specialises in clinical trials of conditions such as Hormone receptor positive HER2 negative breast cancer, Breast cancer, Malignant melanoma, Hormone receptor positive breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Breast Cancer Research

The medical center is at the forefront of breast cancer research, focusing on innovative treatment combinations and targeted therapies. The ongoing studies explore the efficacy of combining capivasertib with CDK4/6 inhibitors and fulvestrant for advanced HR+/HER2- breast cancer, aiming to improve progression-free survival (PFS) in various patient populations.

  • Capivasertib and CDK4/6 Inhibitors
  • MK-2870 and pembrolizumab
  • HER2/neu Peptide GLSI-100

These studies contribute to the development of personalized medicine approaches, enhancing treatment outcomes for patients with specific genetic profiles.

Lung Cancer Innovations

Our center is pioneering research in non-small cell lung cancer (NSCLC) and small-cell lung cancer (SCLC), focusing on novel therapeutic agents like durvalumab. The trials aim to provide continuous treatment options for patients who benefit from previous studies, ensuring safety and tolerability while exploring new frontiers in lung cancer therapy.

  • Durvalumab Roll Over Study
  • EGFR and ALK Wild Type Tumor Pathology
  • Extensive Disease SCLC

These efforts are crucial in advancing the understanding of lung cancer biology and improving long-term patient outcomes.

Melanoma and Skin Cancer

The center is actively engaged in cutting-edge research for melanoma and other skin cancers, investigating the efficacy of novel agents like BNT111 and cemiplimab. These studies aim to enhance the objective response rate (ORR) in patients with late-stage skin cancer, offering hope for those unresponsive to conventional treatments.

  • BNT111 and Cemiplimab Combination
  • Patient Preference for Pembrolizumab

By exploring innovative treatment modalities, the center is contributing to the development of more effective therapies for skin cancer patients.

Gastrointestinal Cancer Research

Our institution is advancing the field of gastrointestinal cancers through research on gastric cancer and gastroesophageal junction adenocarcinoma. The focus is on evaluating the novel agent AZD0901 in comparison to standard treatments, particularly in patients with high levels of Claudin18.2.

  • AZD0901 Efficacy and Safety
  • Claudin18.2 Expression

This research is pivotal in identifying superior treatment options and improving survival rates for patients with advanced gastrointestinal cancers.

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Site location
Ul. Strzalowska 2271-730 SzczecinPoland
Recruiting now
6 trials
Conditions studied
18

More sites in SzczecinPoland

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

18 clinical trials

Breast cancer

Recruiting

Study of BNT327 and a drug combination for patients with untreated metastatic or locally recurrent triple-negative breast cancer

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:BioNTech SE

Study of personalized treatment using drug combination therapy for young women with early stage hormone receptor-positive breast cancer based on gene expression testing

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Phase III Randomized Open‑Label Trial of BNT324 vs Docetaxel Plus Prednisone in Patients with Metastatic Castration‑Resistant Prostate Cancer

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:BioNTech SE

Study Comparing MK-5684 with Abiraterone Acetate or Enzalutamide for Patients with Advanced Prostate Cancer After Hormonal Therapy and Chemotherapy

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone Acetate
  • Sponsor:Merck Sharp & Dohme LLC

Neoplasm+5

Recruiting

Study for Patients with Lung or Urinary Tract Cancer Continuing Treatment with Durvalumab, Infliximab, and Mycophenolate Mofetil

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Durvalumab
  • Sponsor:AstraZeneca AB

Study of Sacituzumab Tirumotecan and Pembrolizumab for Patients with Triple-Negative Breast Cancer Post-Surgery

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Merck Sharp & Dohme LLC

Embolism venous

Not yet recruiting

Safety, Tolerability and Effect of RBD4059 Injection in Adults with Prior VTE After Anticoagulant Therapy and Cancer Patients at High Risk of VTE

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:RBD4059
  • Sponsor:Ribocure Pharmaceuticals AB

Malignant melanoma

Not yet recruiting

Study Comparing MK-7684A (Vibostolimab and Pembrolizumab) with Pembrolizumab for Adults and Children with High-Risk Melanoma

Registered drugNo placebo
Countries:PolandPoland
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Merck Sharp & Dohme LLC

Breast cancer+2

Not recruiting

Gedatolisib plus drug combination for HR‑positive, HER2‑negative advanced breast cancer patients whose disease progressed after CDK4/6 inhibitor therapy

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Alpelisib
  • Sponsor:Celcuity Inc.

A Study of Mevrometostat and Enzalutamide for Men with Metastatic Castration-Sensitive Prostate Cancer Who Have Not Received Hormonal Therapy or Chemotherapy

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Enzalutamide
  • Sponsor:Pfizer Inc.
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Abemaciclib
  • Sponsor:AstraZeneca AB

Study of BNT111 and cemiplimab in patients with advanced melanoma who have not responded to other therapies

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Cemiplimab
  • Sponsor:BioNTech SE
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