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Vojenska Nemocnice Brno

Research site

Czechia Zabrdovicka 3, Zabrdovice, 615 00 Brno, Czechia

  • 26 trials recruiting
  • Colitis ulcerative · Crohn's disease · Atrial fibrillation
  • Adults and children

About Specializations

Vojenska Nemocnice Brno in Brno, Czechia specialises in clinical trials of conditions such as Colitis ulcerative, Crohn's disease, Atrial fibrillation, Cardiac failure, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

At Vojenska Nemocnice Brno, clinical research in cardiovascular diseases focuses on major heart and blood vessel conditions such as acute coronary syndrome, atrial fibrillation, chronic heart failure with reduced ejection fraction, and acute ischemic stroke. These studies are designed to assess new treatment options and compare them with current standard care to better prevent serious events and improve patient outcomes.

  • Research on preventing stroke and systemic embolism in atrial fibrillation
  • Studies evaluating therapies after acute ischemic stroke or high-risk transient ischemic attack
  • Trials aimed at reducing cardiovascular death, heart attack, and other major adverse cardiac events
  • Work in chronic heart failure to improve survival and reduce hospitalizations

Overall, this area of research is centered on testing whether newer therapies can offer better protection against stroke, heart attack, and heart failure complications while maintaining safety.

Digestive System Diseases

The site also supports studies in digestive system diseases, with research mainly centered on moderately to severely active ulcerative colitis. These trials look at ways to ease symptoms such as bowel urgency and improve day-to-day disease control for people living with inflammatory bowel disease.

  • Evaluation of treatments for ulcerative colitis symptom relief
  • Research focused on reducing bowel urgency and improving patient comfort
  • Studies assessing whether new therapies can better control intestinal inflammation

This work reflects a broader effort to improve both symptom management and overall quality of life for patients with chronic gastrointestinal inflammation.

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Site location
Zabrdovicka 3, Zabrdovice615 00 BrnoCzechia
Recruiting now
26 trials
Conditions studied
24

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Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

64 clinical trials

Cardiac failure

Recruiting

Study of maridebart cafraglutide for patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

Phase 2 Randomized Double‑Blind Placebo‑Controlled Study of MH002 in Adults with Mild‑to‑Moderate Ulcerative Colitis Inadequately Controlled by 5‑ASA

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years

Long‑Term Safety and Efficacy of SPY001-001, SPY002 and SPY003 in Adults with Ulcerative Colitis

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:SPY002
  • Sponsor:Spyre Therapeutics Inc.

Crohn's disease

Recruiting

A study to evaluate the effectiveness and safety of duvakitug in patients with moderate to severe Crohn's disease

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Crohn's disease

Recruiting

A study to evaluate the efficacy and safety of duvakitug in patients with moderate to severe Crohn's disease

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

A Study of Long-acting Antibodies SPY001-001 and SPY002 Alone and Combined for Adults with Moderate to Severe Ulcerative Colitis

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:SPY002
  • Sponsor:Spyre Therapeutics Inc.

A study of duvakitug for patients with moderately to severely active ulcerative colitis to see if it works and is safe as maintenance therapy

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

A study testing duvakitug for patients with moderately to severely active ulcerative colitis

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Zilebesiran
  • Sponsor:Alnylam Pharmaceuticals Inc.

Study of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:BI 690517
  • Sponsor:Boehringer Ingelheim Espana S.A.

Crohn's disease

Recruiting

Study of tulisokibart compared to placebo in adults with moderate to severe Crohn's disease

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Tulisokibart
  • Sponsor:Merck Sharp & Dohme LLC

Crohn's disease

Recruiting

Testing SAR442970 compared to placebo in adults with moderate to severe Crohn's disease

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:SAR442970
  • Sponsor:Sanofi-Aventis Recherche & Developpement
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