Vestre Viken HF

At Vestre Viken HF, the Department of oncology is conducting a large body of research in neoplasms, with a major focus on non-small cell lung cancer and other advanced lung tumors. These studies are designed to test new treatment combinations, improve outcomes after standard therapy, and better define which patients may benefit most from targeted and immune-based approaches.

• Advanced and metastatic non-small cell lung cancer
• EGFR-mutated and KRAS G12C-mutated lung cancer
• HER2-driven breast and lung cancers
• Immunotherapy, targeted therapy, and survival improvement studies

This research includes efforts to refine cancer care through precision medicine, evaluate combinations with pembrolizumab and other modern agents, and support better disease control in difficult-to-treat cancers.

The site is also active in breast cancer research, especially for HER2-positive and estrogen receptor-positive disease. The trials aim to improve the effectiveness of treatment before surgery, extend disease control in advanced cancer, and compare new targeted strategies with established care.

• HER2-positive and HER2-negative breast cancer
• Triple-negative breast cancer
• Advanced and resected breast cancer
• Testing targeted and immunotherapy-based treatment approaches

Research in this area reflects a strong interest in matching therapy to tumor biology, with the goal of improving response rates and long-term outcomes for patients with breast cancer.

Clinical trials at the site cover several immune system diseases and chronic inflammatory conditions, including multiple sclerosis, Crohn's disease, and juvenile idiopathic arthritis. These studies are focused on finding better ways to control disease activity, reduce flares, and improve day-to-day function for patients living with long-term immune-related disorders.

• Multiple sclerosis
• Crohn's disease
• Juvenile idiopathic arthritis
• Evaluating disease control, symptom relief, and treatment durability

The research also includes efforts to compare existing therapies with newer options, helping build clearer evidence for safer and more effective management of chronic inflammatory disease.

Another important area of work involves cardiovascular diseases, nutritional and metabolic diseases, and kidney-related complications. Trials here address heart failure, hypertension, obesity, and cardiovascular risk in patients with advanced kidney disease, with the aim of improving prevention and treatment of serious complications.

• Chronic heart failure
• Atherosclerotic cardiovascular disease and type 2 diabetes
• Obesity and cardiovascular safety
• Testing treatment effectiveness and reducing major cardiovascular events

These studies help clarify how newer therapies may lower inflammation, improve heart function, and reduce hospitalizations in patients with complex chronic disease.

The research portfolio also includes studies in nervous system diseases and eye diseases. Key topics include amyotrophic lateral sclerosis, acute ischemic stroke, and central retinal artery occlusion, with trials aimed at improving recovery, slowing disease progression, and expanding treatment options in urgent and high-impact conditions.

• Amyotrophic lateral sclerosis
• Acute ischemic stroke
• Central retinal artery occlusion
• Assessing new therapies for neurological protection and visual recovery

This work reflects a broader effort at Vestre Viken HF to advance care in conditions where faster diagnosis and more effective treatment can make a major difference.

The site conducts trials across respiratory tract diseases, virus diseases, and selected analytical, diagnostic and therapeutic techniques. Studies include COVID-19, COPD, and other respiratory infections, as well as research in surgical care aimed at improving recovery and reducing complications.

• COVID-19 and viral respiratory infection
• Chronic obstructive pulmonary disease
• Supportive care and infection management in hospitalized patients
• Improving surgical outcomes and postoperative recovery

Together, these studies are designed to test better treatment strategies, support safer care, and improve outcomes in both acute illness and perioperative settings.