Universitaetsklinikum Krems

Research in Hemic and Lymphatic Diseases focuses on major blood cancers, especially multiple myeloma and follicular lymphoma. These trials are mainly designed to improve treatment effectiveness, deepen responses, and measure minimal residual disease so doctors can better understand how well therapy is working.

• New approaches for newly diagnosed and relapsed/refractory multiple myeloma
• Studies of maintenance therapy and deeper response assessment, including MRD negativity
• Trials in follicular lymphoma comparing targeted treatment strategies

The site is active in testing therapies that aim to extend remission and refine long-term disease control in hematologic malignancies.

Within Neoplasms, the site is studying several advanced cancers, including non-small cell lung cancer, small cell lung cancer, bladder cancer, prostate cancer, and breast cancer. The main goal is to evaluate new cancer therapies, compare them with current standards, and identify treatments that may improve survival and tumor response.

• Trials in advanced lung cancer, including biomarker-driven and first-line treatment strategies
• Studies for bladder cancer and muscle-invasive bladder cancer focused on treatment effectiveness
• Research in metastatic prostate cancer and ER+/HER2- advanced breast cancer

This oncology program at Universitaetsklinikum Krems emphasizes targeted therapy, immunotherapy, and combination treatment approaches for difficult-to-treat cancers.

Trials in Respiratory Tract Diseases are centered on idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, and other interstitial lung diseases. These studies aim to slow lung function decline, improve symptoms such as cough, and assess whether new therapies can better control chronic fibrotic lung disease.

• Studies in idiopathic pulmonary fibrosis and progressive fibrosing interstitial lung disease
• Research on systemic autoimmune rheumatic disease-associated interstitial lung disease
• Trials evaluating symptom relief, including treatment for persistent cough

This field reflects a strong interest in improving both lung function and day-to-day quality of life for people with chronic pulmonary fibrosis.

The site also conducts research in Immune System Diseases, including ulcerative colitis and Crohn's disease. These trials are designed to test new therapies that may reduce inflammation, improve disease control, and support better long-term management of chronic immune-related conditions.

• Studies of ulcerative colitis aimed at improving induction and maintenance treatment
• Trials in Crohn's disease assessing control of active disease
• Research focused on safer and more effective immune-targeted therapies

At Universitaetsklinikum Krems, this area complements the oncology portfolio by advancing therapies that modulate immune activity in a clinically meaningful way.