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Universitaetsklinikum Knappschaftskrankenhaus Bochum GmbH

Research site

Germany In Der Schornau 23-25, Langendreer, 44892 Bochum, Germany

  • 20 trials recruiting
  • Acute myeloid leukaemia · Glioblastoma · Metabolic dysfunction-associated steatohepatitis
  • Adult patients

About Specializations

Universitaetsklinikum Knappschaftskrankenhaus Bochum GmbH in Bochum, Germany specialises in clinical trials of conditions such as Acute myeloid leukaemia, Glioblastoma, Metabolic dysfunction-associated steatohepatitis, Myelodysplastic syndrome, and other specialisations. This site conducts important research.

Main research areas of the site

Hematologic Malignancies

The medical center is at the forefront of research in hematologic malignancies, focusing on innovative therapies for conditions such as acute myeloid leukemia (AML) and myelodysplastic syndrome. The center's trials explore the efficacy of novel drug combinations and personalized treatment approaches to improve patient outcomes.

  • Acute Myeloid Leukemia (AML)
  • Myelodysplastic Syndrome
  • Acute Lymphoblastic Leukemia (ALL)

By integrating cutting-edge research with clinical practice, the center aims to enhance survival rates and quality of life for patients with these challenging conditions.

Neuro-Oncology

Specializing in neuro-oncology, the center conducts pivotal studies on glioblastoma and medulloblastoma. Research efforts are directed towards developing personalized therapies and improving the efficacy of existing treatment protocols.

  • Glioblastoma
  • Medulloblastoma
  • Grade 2 or 3 Glioma

The center's commitment to advancing neuro-oncological care is evident in its exploration of novel therapeutic agents and vaccination strategies.

Critical Care Medicine

In the realm of critical care medicine, the center is pioneering research on sedation practices and adjunctive therapies for critically ill patients. Studies focus on optimizing sedation protocols and evaluating new treatment options for conditions like sepsis and septic shock.

  • Sepsis and Septic Shock
  • Critical Care Sedation

These efforts aim to improve patient outcomes in intensive care settings by refining therapeutic strategies and enhancing patient safety.

Gastrointestinal Oncology

The center is actively involved in research on gastrointestinal oncology, with a focus on hepatocellular carcinoma and esophagogastric adenocarcinoma. Trials investigate the efficacy of novel drug combinations and treatment modalities to improve survival rates and quality of life.

  • Hepatocellular Carcinoma
  • Esophagogastric Adenocarcinoma
  • Rectal Cancer

Through these studies, the center aims to advance therapeutic options and provide evidence-based care for patients with complex gastrointestinal cancers.

Lymphoma Research

Focusing on lymphoma research, the center explores innovative treatment regimens for B-cell lymphoma and primary CNS lymphoma. The trials aim to assess the efficacy of novel therapeutic agents and optimize treatment protocols for better patient outcomes.

  • Aggressive B-cell Lymphoma
  • Primary CNS Lymphoma

By advancing research in this field, the center contributes to the development of more effective and targeted therapies for lymphoma patients.

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Site location
In Der Schornau 23-25, Langendreer44892 BochumGermany
Recruiting now
20 trials
Conditions studied
29

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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32 clinical trials

A Phase III Study of Survodutide in Adults with Compensated NASH Cirrhosis to Assess Liver Outcomes and Safety

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:BI 456906
  • Sponsor:Boehringer Ingelheim International GmbH

A Phase III trial of BI 456906 weekly injections in adults with NASH and stage 2‑3 liver fibrosis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:BI 456906
  • Sponsor:Boehringer Ingelheim International GmbH

Accelerating improvement with teclistamab plus standard drug combination in newly diagnosed transplant‑eligible multiple myeloma patients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bortezomib
  • Sponsor:Universitaetsklinikum Heidelberg AöR

Frexalimab versus Tacrolimus for Prevention of Kidney Transplant Rejection in Adult Kidney Transplant Recipients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Frexalimab
  • Sponsor:Sanofi-Aventis Recherche & Developpement

A study of bleximenib combined with intensive chemotherapy for adults with newly diagnosed acute myeloid leukemia with specific genetic changes.

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bleximenib
  • Sponsor:Haemato Oncology Foundation For Adults Netherlands

A Study of Tenecteplase for Acute Ischemic Stroke in Patients Taking Direct Oral Anticoagulants

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Tenecteplase
  • Sponsor:University Medical Center Hamburg-Eppendorf

Study comparing standard and reduced intensity treatment in patients with acute myeloid leukemia or chronic lymphocytic leukemia who have no detectable disease after initial therapy

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Busulfan
  • Sponsor:Medizinische Hochschule Hannover

Study on Ivosidenib, Azacitidine, and Venetoclax for Adults with Newly Diagnosed IDH1-Mutated Acute Myeloid Leukemia Ineligible for Intensive Chemotherapy

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Haemato Oncology Foundation For Adults Netherlands

Study on Revumenib, Azacitidine, and Venetoclax for Adults with Newly Diagnosed Acute Myeloid Leukemia Not Eligible for Intensive Chemotherapy

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Haemato Oncology Foundation For Adults Netherlands

Glioma

Recruiting

Study of Temozolomide and Lomustine Followed by Radiotherapy versus Standard Treatment in Patients with Newly Diagnosed Grade 2 or 3 Glioma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Lomustine
  • Sponsor:Universitaetsklinikum Heidelberg AöR

Study on Atezolizumab and Bevacizumab for Patients with Intermediate-Stage Liver Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Atezolizumab
  • Sponsor:Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbH

Study on Ponatinib and Imatinib for Adults with Philadelphia-Chromosome Positive Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Blinatumomab
  • Sponsor:Goethe University Frankfurt
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