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Umhat Sveta Marina - Pleven OOD

Research site

Bulgaria Bulgarian Aviation Street 1, 5800 Pleven, Bulgaria

  • 2 trials recruiting
  • Metabolic dysfunction-associated liver disease · Non-small cell lung cancer · Peripheral arterial occlusive disease
  • Adult patients

About Specializations

Umhat Sveta Marina - Pleven OOD in Pleven, Bulgaria specialises in clinical trials of conditions such as Metabolic dysfunction-associated liver disease, Non-small cell lung cancer, Peripheral arterial occlusive disease, and other specialisations. This site conducts important research.

Main research areas of the site

Oncology – Advanced Lung Cancer

In the Department of Medical Oncology, researchers are evaluating novel targeted agents for KRAS p.G12C positive non‑small cell lung cancer.

  • Targeted KRAS inhibition
  • Combination chemo‑immunotherapy
  • Survival outcome assessment

The study compares sotorasib combined with chemotherapy to pembrolizumab‑based regimens, aiming to improve progression‑free survival and overall outcomes for patients with advanced disease.

Metabolic Diseases – Liver Health

A dedicated program investigates therapeutic strategies for Metabolic Dysfunction‑Associated Steatotic Liver Disease.

  • Multi‑agent metabolic protocols
  • Outcome‑focused liver assessments
  • Reduction of major adverse liver events

Conducted at Umhat Sveta Marina - Pleven OOD, the master protocol evaluates several agents to determine whether the new approach can lower the incidence of serious liver complications.

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Site location
Bulgarian Aviation Street 15800 PlevenBulgaria
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Recruiting now
2 trials
Conditions studied
3

More sites in PlevenBulgaria

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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3 clinical trials

Non-small cell lung cancer

Recruiting

Comparing sotorasib and pembrolizumab with chemotherapy for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Amgen Inc.

Metabolic dysfunction-associated liver disease

Recruiting

N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:LY3437943 sodium
  • Sponsor:Eli Lilly & Co.

Peripheral arterial occlusive disease

Not yet recruiting

Efficacy and Safety of REGN7508, REGN9933, and Rivaroxaban in Adults with Peripheral Artery Disease after Recent Lower‑Extremity Revascularization

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:REGN7508
  • Sponsor:Regeneron Pharmaceuticals Inc.
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