St James’s Centre at St Luke’s Radiation Oncology Network

At St James’s Centre at St Luke’s Radiation Oncology Network, clinical research is focused on neoplasms within radiation oncology, with studies exploring better ways to treat difficult-to-manage cancers and improve patient outcomes.

• Oropharyngeal cancer: evaluating alternative treatment approaches to improve survival, swallowing function, and quality of life
• Prostate cancer: studying new ways to strengthen standard therapy for very high-risk, localized disease

These trials are designed to assess treatment effectiveness, refine supportive care outcomes, and support more informed decisions for patients facing complex cancer care.

Research at this Dublin site includes oropharyngeal cancer studies in the head and neck cancer area, with a focus on comparing treatment options for people with intermediate and high-risk disease.

• Improving overall survival with alternative treatment regimens
• Assessing toxicity, swallowing outcomes, and quality of life after treatment

The goal is to identify approaches that preserve function while still delivering effective cancer control.

The site is also involved in research on localized very high-risk prostate cancer, examining whether adding new treatment strategies to androgen deprivation therapy and radiation can improve disease control.

• Testing whether treatment intensification can improve metastasis-free survival
• Supporting better outcomes for patients with aggressive, localized prostate cancer

These studies aim to strengthen standard care and reduce the chance of cancer spread or death.