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Spitalul Clinic Filantropia

Research site

Romania Bulevardul Mihalache Ion 11-13, 011171 Bucharest, Romania

  • 9 trials recruiting
  • Breast cancer · Triple negative breast cancer · Contraception
  • Adults and children

About Specializations

Spitalul Clinic Filantropia in Bucharest, Romania specialises in clinical trials of conditions such as Breast cancer, Triple negative breast cancer, Contraception, Hormone receptor positive breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Breast Cancer Research

The medical center is at the forefront of breast cancer research, focusing on innovative treatments for cases that cannot be surgically removed. The center is conducting a pivotal clinical trial comparing the efficacy of MK-2870 with or without pembrolizumab against traditional chemotherapy.

  • Hormone receptor positive breast cancer
  • Progression-free survival (PFS) assessment
  • RECIST 1.1 criteria evaluation

This research aims to enhance therapeutic options and improve outcomes for patients with advanced breast cancer.

Gynecological Infections

Specializing in the treatment of vaginitis, the center is conducting a comprehensive study to establish the non-inferiority of a new combination therapy of metronidazole, Neomycin Sulfate, and nystatin compared to existing treatments. This research is crucial for addressing both specific and non-specific vaginitis.

  • Bacterial vaginosis (BV)
  • Vulvovaginal candidiasis (VVC)
  • Clinical and microbiologic/mycological cure

The study's findings are expected to provide safer and more effective treatment options for female patients.

Triple-Negative Breast Cancer

The center is advancing the treatment of triple-negative breast cancer through a study comparing sacituzumab govitecan-hziy with the treatment of physician's choice. This research is particularly focused on patients with previously untreated locally advanced inoperable or metastatic conditions.

  • PD-L1-negative metastatic triple-negative breast cancer
  • PD-L1-positive metastatic triple-negative breast cancer
  • Anti-PD-(L)1 agent pre-treated patients

The study aims to improve progression-free survival rates and offer new hope for patients with challenging cancer profiles.

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Site location
Bulevardul Mihalache Ion 11-13011171 BucharestRomania
Recruiting now
9 trials
Conditions studied
15

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Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

21 clinical trials

Contraception+1

Recruiting

Contraceptive efficacy, safety and tolerability of drospirenone 4 mg (LPRI‑CF113) in healthy women of reproductive age over 13 cycles

InvestigationalNo placebo
Countries:RomaniaRomania
  • Participants:0–17 years · 18–64 years · Healthy volunteers
  • Substances:Drospirenone
  • Sponsor:Chemo Research S.L.

Breast cancer+1

Recruiting

Study on the Effectiveness of GP2 and Sargramostim for HER2 Positive Breast Cancer Patients with Residual Disease or High-Risk After Standard Therapy

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Sargramostim
  • Sponsor:Greenwich LifeSciences Inc.

A study of palazestrant and ribociclib compared to letrozole and ribociclib for patients with advanced ER+ HER2- breast cancer

Registered drug
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Letrozole
  • Sponsor:Olema Pharmaceuticals Inc.

Breast cancer+2

Recruiting

A Study Comparing RLY-2608 and Fulvestrant with Capivasertib and Fulvestrant for Patients with PIK3CA-Mutant Hormone Receptor Positive, HER2-Negative Advanced Breast Cancer

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Capivasertib
  • Sponsor:Relay Therapeutics Inc.

Study of sacituzumab tirumotecan, pembrolizumab and chemotherapy combination for early-stage triple-negative breast cancer or hormone receptor-low positive/HER2-negative breast cancer

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Merck Sharp & Dohme LLC

Evaluating sacituzumab tirumotecan alone or with pembrolizumab compared to standard treatment in untreated patients with metastatic triple-negative breast cancer with low PD-L1 expression

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Merck Sharp & Dohme LLC

Study of Sacituzumab Tirumotecan and Bevacizumab for Patients with Recurrent Ovarian Cancer

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Merck Sharp & Dohme LLC

Study Comparing MK-2870 and Pembrolizumab with Chemotherapy for Patients with Advanced Hormone Receptor Positive Breast Cancer

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Merck Sharp & Dohme LLC

Breast cancer

Recruiting

Study on the Effectiveness of Inavolisib with Trastuzumab and Pertuzumab for Patients with HER2-Positive, HR-Positive, PIK3CA Mutant Early Breast Cancer

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Inavolisib
  • Sponsor:GBG Forschungs GmbH

Vulvovaginal candidiasis+1

Not yet recruiting

Study on the Effectiveness and Safety of Metronidazole, Neomycin Sulfate, and Nystatin for Women with Bacterial Vaginosis and Yeast Infections

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years
  • Substances:Metronidazole
  • Sponsor:Antibiotice S.A.

Contraception

Not recruiting

Study on the Effectiveness and Safety of Levonorgestrel Vaginal Delivery System vs. Desogestrel Tablets for Preventing Pregnancy in Women

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · Healthy volunteers
  • Substances:Desogestrel
  • Sponsor:Chemo Research S.L.
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Abemaciclib
  • Sponsor:AstraZeneca AB
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