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Specialized Hospital For Active Treatment Of Pneumo-Physiatiric Diseases Vraca /Sbalpfz Vratsa EOOD

Research site

Bulgaria Ulitsa General Leonov 93, 3000 Vratsa, Bulgaria

  • 2 trials recruiting
  • Asthma · Chronic obstructive pulmonary disease · Bronchiectasis
  • Adults and children

About Specializations

Specialized Hospital For Active Treatment Of Pneumo-Physiatiric Diseases Vraca /Sbalpfz Vratsa EOOD in Vratsa, Bulgaria specialises in clinical trials of conditions such as Asthma, Chronic obstructive pulmonary disease, Bronchiectasis, COVID-19, and other specialisations. This site conducts important research.

Main research areas of the site

Respiratory Tract Diseases Research

At the Specialized Hospital For Active Treatment Of Pneumo-Physiatiric Diseases Vraca /Sbalpfz Vratsa EOOD, most studies focus on respiratory tract diseases, especially asthma, chronic obstructive pulmonary disease, and bronchiectasis. The trials are designed to improve symptom control, reduce flare-ups, and test whether newer inhaled or biologic therapies can offer better long-term outcomes for people with persistent lung disease.

  • Studies in asthma are looking at better control for moderate to severe and inadequately controlled disease
  • Research in COPD is evaluating ways to reduce exacerbations and support breathing function
  • Trials in bronchiectasis are testing treatments aimed at lowering pulmonary exacerbations

This work reflects a strong clinical interest in helping patients with chronic airway conditions through improved treatment effectiveness and disease management.

Virus Diseases and COVID-19 Studies

The site also conducts research in virus diseases, with attention to SARS-CoV-2 infection and related pediatric care. These trials explore antiviral treatment options and safety in younger patients, with the goal of supporting recovery and preventing progression to more severe illness.

  • SARS-CoV-2 infection studies are assessing antiviral treatment use in children and adolescents
  • Research is focused on safety, tolerability, and treatment effectiveness in nonhospitalized patients at risk
  • The overall aim is to improve care for pediatric COVID-19 cases

These studies add an important infectious disease component to the Pneumology Department portfolio in Vratsa.

Immune System Phenomena in Chronic Lung Disease

Another key area of research involves immune system phenomena, especially inflammation-driven disease patterns in asthma and COPD. Trials here are examining whether targeted therapies can better control airway inflammation, improve lung function, and reduce the risk of repeated exacerbations.

  • In asthma, studies are evaluating control of inflammation and protection against lung function decline
  • In COPD, research is testing approaches to reduce exacerbation frequency in patients with ongoing symptoms
  • Some studies are exploring biomarkers such as FeNO to better understand treatment response

The research profile shows a clear emphasis on immune-linked respiratory conditions and the search for more precise, effective treatment strategies.

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Site location
Ulitsa General Leonov 933000 VratsaBulgaria
Recruiting now
2 trials
Conditions studied
4

More sites in VratsaBulgaria

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

15 clinical trials

Bronchiectasis

Recruiting

Study of BI 1291583 tablets taken once daily for 76 weeks in adults with bronchiectasis

Investigational
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:BI 1291583
  • Sponsor:Boehringer Ingelheim Espana S.A.

Study on the Effects of Budesonide, Glycopyrronium, and Formoterol Fumarate for Patients with Chronic Obstructive Pulmonary Disease (COPD)

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:AstraZeneca AB

Asthma

Not yet recruiting

Asthma in adults: beclometasone dipropionate, formoterol fumarate dihydrate, and glycopyrronium bromide compared with beclometasone dipropionate and formoterol fumarate dihydrate

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Beclometasone Dipropionate
  • Sponsor:Chiesi Farmaceutici S.p.A.

Asthma

Not recruiting

Study on the Effectiveness and Safety of Fluticasone Propionate and Salbutamol Sulfate for Asthma in Patients Aged 12 and Older

Investigational
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Salbutamol Sulfate
  • Sponsor:Teva Branded Pharmaceutical Products R&D LLC

Study on the Effects of Budesonide, Glycopyrronium, and Formoterol in Patients Aged 40-80 with Chronic Obstructive Pulmonary Disease (COPD)

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:AstraZeneca AB

Study on the Effects of Astegolimab and Drug Combination for Patients with Chronic Obstructive Pulmonary Disease (COPD)

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Sponsor:Genentech Inc.

A study testing tozorakimab for long-term treatment of chronic obstructive pulmonary disease in former smokers with repeated flare-ups

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Salbutamol
  • Sponsor:AstraZeneca AB

Study of Tozorakimab for Patients with Chronic Obstructive Pulmonary Disease Who Have Symptoms and a History of Flare-ups

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Salbutamol Sulfate
  • Sponsor:AstraZeneca AB

Asthma

Not recruiting

Study on GSK5784283 for Adults Aged 18-75 with Uncontrolled Asthma

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:GSK5784283
  • Sponsor:Glaxosmithkline Research & Development Limited

Asthma

Not recruiting

Study on the Effectiveness and Safety of Budesonide, Glycopyrronium, and Formoterol Inhaler for Adults and Adolescents with Severe Asthma Not Well Controlled

Registered drug
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:AstraZeneca AB

Asthma

Not recruiting

Study on the Effectiveness and Safety of Fluticasone Propionate and Salbutamol Sulfate for Patients with Asthma

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Salbutamol Sulfate
  • Sponsor:Teva Branded Pharmaceutical Products R&D LLC

COVID-19

Not recruiting

Study on the Safety and Effectiveness of Nirmatrelvir and Ritonavir for Nonhospitalized Children with COVID-19 at Risk of Severe Illness

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years
  • Substances:Nirmatrelvir
  • Sponsor:Pfizer Inc.
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