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Specialized Hospital For Active Cardiology Treatement Cardiolife OOD

Research site

Bulgaria Bulevard Republika 15, 9009 Varna, Bulgaria

  • 4 trials recruiting
  • Arteriosclerosis · Hypertriglyceridaemia · Obesity
  • Adult patients

About Specializations

Specialized Hospital For Active Cardiology Treatement Cardiolife OOD in Varna, Bulgaria specialises in clinical trials of conditions such as Arteriosclerosis, Hypertriglyceridaemia, Obesity, Acute myocardial infarction, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

The Specialized Hospital For Active Cardiology Treatement Cardiolife OOD in Varna, Bulgaria is conducting research in cardiology focused on cardiovascular diseases, including myocardial infarction, atherosclerotic cardiovascular disease, and heart failure. These trials are designed to test new treatment options and assess whether they can lower the risk of major heart-related events and improve outcomes for patients with serious cardiac conditions.

  • Research on acute myocardial infarction is evaluating whether a new anti-inflammatory approach can reduce major adverse cardiovascular events after a heart attack.
  • Studies in atherosclerosis and ASCVD are examining therapies aimed at improving long-term cardiovascular risk control.
  • Trials in heart failure are assessing new options for patients with reduced exercise tolerance and ongoing symptoms.

Overall, this area of research is centered on improving prevention, treatment effectiveness, and safety in patients with high-risk heart disease.

Congenital, Hereditary, and Neonatal Diseases

Within the broader congenital, hereditary, and neonatal disease category, the site is contributing to research on non-ischemic cardiomyopathy and related forms of congestive heart failure. The work focuses on testing innovative therapies that may support heart function and help patients with advanced symptoms manage their condition more effectively.

  • Studies in non-ischemic cardiomyopathy are exploring whether a novel gene-based treatment can improve symptoms and cardiac performance.
  • Research in advanced heart failure is evaluating new approaches for patients with persistent limitations despite standard care.

This line of research reflects an interest in developing more targeted options for structural and inherited heart conditions.

Nutritional and Metabolic Diseases

The site also supports trials in nutritional and metabolic diseases, with a strong focus on hypertriglyceridemia, severe hypertriglyceridemia, and obesity-related heart disease. These studies are intended to evaluate whether new therapies can better control lipid levels and reduce the cardiovascular risks linked to metabolic disorders.

  • Trials in hypertriglyceridemia are testing treatments aimed at lowering fasting triglyceride levels.
  • Research in severe hypertriglyceridemia is examining safety, tolerability, and lipid-lowering benefit.
  • Studies involving heart failure with obesity are looking at whether treatment can reduce worsening heart failure events.

These investigations highlight a practical effort to improve metabolic control and reduce downstream cardiovascular complications.

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Site location
Bulevard Republika 159009 VarnaBulgaria
Recruiting now
4 trials
Conditions studied
10

More sites in VarnaBulgaria

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

10 clinical trials

Obesity+2

Recruiting

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years
  • Substances:POLYPEPTIDE CONSISTING OF A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND AN AMYLIN RECEPTOR AGONIST, CONNECTED BY A LINKER WITH 4 GLYCINE RESIDUES, AND CONNECTED TO A C18 FATTY ACID SIDE CHAIN
  • Sponsor:Novo Nordisk A/S

Cardiac failure+1

Recruiting

Study of Zenagamtide (NNC0487-0111) versus placebo in patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:POLYPEPTIDE CONSISTING OF A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND AN AMYLIN RECEPTOR AGONIST, CONNECTED BY A LINKER WITH 4 GLYCINE RESIDUES, AND CONNECTED TO A C18 FATTY ACID SIDE CHAIN
  • Sponsor:Novo Nordisk A/S

Study of AP31969 compared to placebo to control heart rhythm in patients with atrial fibrillation

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AP31969 sulfate
  • Sponsor:Acesion Pharma ApS
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Finerenone
  • Sponsor:Colorado Prevention Center

Study of ISIS 678354 for Patients with Severe High Triglycerides

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:ISIS 678354 sodium salt
  • Sponsor:Ionis Pharmaceuticals Inc.

Arteriosclerosis

Not recruiting

Study on the Effect of Obicetrapib in Patients with Atherosclerotic Cardiovascular Disease Not Adequately Managed by Current Lipid-Lowering Treatments

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Obicetrapib
  • Sponsor:NewAmsterdam Pharma B.V.

Hypertriglyceridaemia+1

Not recruiting

Study of Olezarsen (ISIS 678354) for Patients with High Triglycerides and Heart Disease or Severe High Triglycerides

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:ISIS 678354 sodium salt
  • Sponsor:Ionis Pharmaceuticals Inc.

Hypertriglyceridaemia

Not recruiting

Study of ISIS 678354 for Patients with Severe Hypertriglyceridemia

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:ISIS 678354 sodium salt
  • Sponsor:Ionis Pharmaceuticals Inc.

A study of ziltivekimab compared to placebo for reducing heart problems in patients who have had a heart attack

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Ziltivekimab
  • Sponsor:Novo Nordisk A/S

Study of AB-1002 gene therapy given through coronary arteries in adults with severe (NYHA Class III) heart failure caused by non-ischemic cardiomyopathy

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AB-1002
  • Sponsor:Askbio Inc.
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