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Siteworks GmbH

Verified siteinfo

Germany Ettlinger Strasse 5a, Suedstadt, 76137 Karlsruhe, Germany

  • 10 trials recruiting
  • Overweight · Obesity · Obstructive sleep apnoea syndrome
  • Adults and children

About Specializations

Siteworks GmbH in Karlsruhe, Germany specialises in clinical trials of conditions such as Overweight, Obesity, Obstructive sleep apnoea syndrome, Osteoarthritis, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

At Siteworks GmbH investigators are exploring innovative approaches to reduce cardiovascular risk in patients with obesity and related conditions.

  • Atherosclerotic cardiovascular disease
  • Hypercholesterolaemia
  • Established ASCVD

These studies aim to test new therapies that lower LDL‑C, improve heart outcomes, and support weight management.

Digestive System Diseases

Research focuses on functional gastrointestinal disorders, especially diarrhoea‑predominant irritable bowel syndrome.

  • Diarrhoea‑dominant IBS
  • Functional bowel discomfort
  • Gut motility abnormalities

The goal is to evaluate novel agents that provide symptom relief and improve quality of life.

Hormonal diseases

The site conducts trials on hormone‑related hair loss in women, addressing androgenetic alopecia.

  • Female androgenetic alopecia
  • Hormone‑imbalanced hair loss

These studies assess oral minoxidil and topical formulations to restore hair density.

Musculoskeletal Diseases

Investigations target joint pain and osteoarthritis, particularly in patients with excess weight.

  • Knee osteoarthritis
  • Chronic non‑specific low back pain
  • Weight‑related musculoskeletal discomfort

Therapies aim to achieve pain reduction and enhance mobility while addressing obesity.

Nervous System Diseases

Neurological research includes obstructive sleep apnea and its impact on brain health.

  • Moderate to severe OSA
  • Insomnia disorder
  • Sleep‑apnea related cognitive issues

Trials evaluate drugs and devices designed to improve sleep quality and lessen daytime fatigue.

Nutritional and Metabolic Diseases

Metabolic studies address overweight, obesity and type 2 diabetes, seeking effective weight‑loss solutions.

  • Obesity without diabetes
  • Obesity with type 2 diabetes
  • Weight‑management in metabolic syndrome

Research tests compounds that promote body‑weight reduction and improve glycaemic control.

Respiratory Tract Diseases

Respiratory trials evaluate asthma therapies and vaccine candidates against viral infections.

  • Asthma
  • Influenza
  • RSV and HMPV infections

The aim is to demonstrate efficacy of inhaled treatments and protective vaccine efficacy in older adults.

Skin and Connective Tissue Diseases

Skin research includes studies on hair loss and related connective‑tissue conditions.

  • Female androgenetic alopecia
  • Hormone‑imbalanced hair thinning

Outcomes focus on hair count improvement and patient satisfaction.

Virus Diseases

The laboratory investigates viral pathogens, testing vaccines for influenza and respiratory syncytial virus.

  • Influenza vaccine
  • RSV protein vaccine
  • Human metapneumovirus (HMPV) vaccine

These studies aim to protect high‑risk seniors and reduce severe respiratory illness.

Mental Disorders

Psychiatric research at the site evaluates botanical and non‑pharmacologic treatments for major depressive disorder.

  • Mild to moderate MDD
  • Insomnia associated with depression
  • Depression rating scale outcomes

The objective is to show symptom improvement and higher remission rates.

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Site location
Ettlinger Strasse 5a, Suedstadt76137 KarlsruheGermany
Recruiting now
10 trials
Conditions studied
17
Partner status
Verified site

More sites in KarlsruheGermany

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

21 clinical trials

Obesity+2

Recruiting

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational
Countries:GermanyGermany
  • Participants:18–64 years
  • Sponsor:Novo Nordisk A/S

Study on the Effects of Baxdrostat and Dapagliflozin in Adults with Chronic Kidney Disease and High Blood Pressure

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:AstraZeneca AB

A Phase 3 Randomized, Double-blind,Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants with Obstructive Sleep Apnea not on Positive Airway Pressure Therapy and Living with Overweight or Obesity (MARITIME-OSA-2)

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

Influenza+1

Recruiting

Efficacy and safety of the investigational mRNA influenza vaccine gskvx000000077430 (drug combination) in adults ≥ 65 years

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:65+ years · Healthy volunteers
  • Substances:INFLUENZA A VIRUS, A/CROATIA/10136RV/2023 (H3N2) LIKE STRAIN X-425A, INACTIVATED
  • Sponsor:GlaxoSmithKline Biologicals

Obesity+2

Recruiting

Study of the efficacy and safety of Eloralintide in adults with knee osteoarthritis and overweight or obesity

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:LY3841136 sodium
  • Sponsor:Eli Lilly & Co.

A study to evaluate the effects of zenagamtide in people with overweight or obesity and obstructive sleep apnoea not treated with positive airway pressure

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Novo Nordisk A/S

Study of zenagamtide for weight loss and sleep improvement in patients with obesity and obstructive sleep apnea using positive airway pressure therapy

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Novo Nordisk A/S

Study of Maridebart Cafraglutide for Adults with Obstructive Sleep Apnea and Overweight or Obesity Who Use Positive Airway Pressure Therapy

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

Osteoarthritis

Recruiting

A Study of Orforglipron for Knee Pain Relief in Adults with Obesity or Overweight and Knee Osteoarthritis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Eli Lilly & Co.

Study on the Effectiveness and Safety of Myrrh, Coffee Charcoal, and Chamomile Extract for Patients with Diarrhea-Predominant Irritable Bowel Syndrome

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Coffee Charcoal
  • Sponsor:REPHA GmbH Biologische Arzneimittel

Hypercholesterolaemia

Not yet recruiting

Effect of laroprovstat/rosuvastatin combination versus laroprovstat, rosuvastatin, and placebo on LDL‑C in hypercholesterolemia patients not previously treated with lipid‑lowering therapy

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Laroprovstat
  • Sponsor:AstraZeneca AB

Obesity+1

Not yet recruiting

Phase 3 Double‑Blind Study of Olatorepatide for Weight Loss in Adults with Overweight or Obesity Without Diabetes

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Regeneron Pharmaceuticals Inc.
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