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Samodzielny Publiczny Zaklad Opieki Zdrowotnej Centralny Szpital Kliniczny Uniwersytetu Medycznego W Lodzi

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Poland Ul. Pomorska Nr 251, 92-213 Lodz, Poland

  • 41 trials recruiting
  • Chronic kidney disease · Atrial fibrillation · IgA nephropathy
  • Adults and children

About Specializations

Samodzielny Publiczny Zaklad Opieki Zdrowotnej Centralny Szpital Kliniczny Uniwersytetu Medycznego W Lodzi in Lodz, Poland specialises in clinical trials of conditions such as Chronic kidney disease, Atrial fibrillation, IgA nephropathy, Colitis ulcerative, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases and Heart Failure Research

At Samodzielny Publiczny Zaklad Opieki Zdrowotnej Centralny Szpital Kliniczny Uniwersytetu Medycznego W Lodzi, clinical trials in cardiovascular diseases focus on major conditions such as acute coronary syndrome, atrial fibrillation, heart failure, and hypertension. The research is aimed at improving event prevention, supporting better symptom control, and evaluating new treatment strategies for people at high cardiovascular risk.

  • Reducing the risk of heart attacks, stroke, and other major cardiovascular events
  • Improving treatment options for atrial fibrillation and related clotting risk
  • Studying therapies for heart failure, including worsening and acute forms

These studies reflect a strong interest in practical advances that may help lower complications and improve long-term outcomes in patients with serious heart and blood vessel disease.

Kidney and Immune-Mediated Diseases

This site conducts extensive research in renal diseases and immune system disorders, especially IgA nephropathy, lupus nephritis, membranous nephropathy, and other chronic kidney conditions. Many trials are designed to test new therapies that may slow kidney damage, reduce proteinuria, and preserve kidney function over time.

  • Evaluating treatments for IgA nephropathy and other glomerular diseases
  • Studying approaches to slow chronic kidney disease progression
  • Testing therapies for lupus nephritis and related autoimmune kidney involvement

The research portfolio also includes work on kidney-related symptoms and complications, showing a broad effort to improve both disease control and everyday quality of life.

Gastroenterology and Inflammatory Bowel Disease

Clinical trials in digestive system diseases at this hospital cover ulcerative colitis and Crohn’s disease, with a particular emphasis on moderate to severe disease in both adults and children. The main purpose is to assess new and established therapies that may improve remission rates, maintain disease control, and reduce inflammatory burden.

  • Testing treatments for ulcerative colitis and Crohn’s disease
  • Exploring options for pediatric and adult inflammatory bowel disease care
  • Evaluating therapies intended to improve remission and long-term disease management

These studies support ongoing efforts to offer more effective and better-tolerated care for people living with chronic intestinal inflammation.

Hematology and Oncology

The site also participates in research on blood diseases and neoplasms, including acute lymphoblastic leukemia and lymphoblastic lymphoma. The trials are focused on improving survival, reducing relapse, and refining treatment approaches for children and adolescents with aggressive blood cancers.

  • Studying treatment strategies for acute lymphoblastic leukemia
  • Investigating care for lymphoblastic lymphoma
  • Aiming to improve remission outcomes and reduce treatment-related complications

This area highlights the center’s role in pediatric and adolescent cancer research, with an emphasis on better disease control and safer care.

Neurology, Psychiatry, and Cognitive Disorders

Research in nervous system diseases and mental disorders includes trials in Alzheimer’s disease, schizophrenia, depression, anxiety, and attention-deficit hyperactivity disorder. These studies are designed to assess new options for symptom relief, cognitive support, and long-term safety in patients with complex brain and mental health conditions.

  • Evaluating therapies for Alzheimer’s disease and mild cognitive impairment
  • Studying treatment approaches for schizophrenia and treatment-resistant symptoms
  • Exploring care for depression, anxiety, and related psychiatric conditions

These trials show a broad commitment to advancing both neurological and psychiatric care through improved treatment effectiveness and safety.

Pediatric and Autoimmune Disorders

The research program includes several studies in autoimmune diseases, musculoskeletal diseases, and congenital conditions, such as juvenile psoriatic arthritis, systemic lupus erythematosus, hereditary angioedema, and osteogenesis imperfecta. The focus is on testing therapies that may improve disease control, reduce symptoms, and support safer long-term management in younger patients.

  • Testing treatments for juvenile psoriatic arthritis and other pediatric inflammatory disorders
  • Studying immune-targeted therapies for systemic lupus erythematosus
  • Evaluating new options for hereditary angioedema and osteogenesis imperfecta

At the Lodz site, these trials add an important pediatric and autoimmune dimension to the broader clinical research portfolio.

Metabolic, Infectious, and Other Internal Medicine Studies

Additional trials cover nutritional and metabolic diseases, respiratory tract diseases, bacterial infections, and other internal medicine conditions. Key areas include type 2 diabetes, obesity, asthma, and complicated urinary infections, with research aimed at improving treatment effectiveness and disease control.

  • Assessing therapies for type 2 diabetes and metabolic risk
  • Studying interventions for asthma and other respiratory conditions
  • Evaluating treatment options for complicated urinary tract infections and other infections

These studies show the site’s wide clinical reach beyond cardiology, supporting research across common chronic illnesses and acute medical problems.

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Site location
Ul. Pomorska Nr 25192-213 LodzPoland
Recruiting now
41 trials
Conditions studied
62
Partner status
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Ongoing trials

Clinical trials currently enrolling participants at this site.

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106 clinical trials

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

Renal disorder

Recruiting

BI 764198 in Adults and Adolescents with Proteinuric Kidney Diseases

Investigational
Countries:PolandPoland
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:[4-(6-Aminopyridazin-3-Yl)Piperidin-1-Yl][5-(4-Fluorophenoxy)-4-Methoxypyridin-2-Yl]Methanone
  • Sponsor:Boehringer Ingelheim Espana S.A.

A study to evaluate the effects of BI 764198 in adults and adolescents with focal segmental glomerulosclerosis (FSGS)

Investigational
Countries:PolandPoland
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:[4-(6-Aminopyridazin-3-Yl)Piperidin-1-Yl][5-(4-Fluorophenoxy)-4-Methoxypyridin-2-Yl]Methanone
  • Sponsor:Boehringer Ingelheim Espana S.A.

Asthma

Recruiting

Study to evaluate the long-term safety and effectiveness of lunsekimig in adults with moderate to severe asthma

InvestigationalNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Zilebesiran
  • Sponsor:Alnylam Pharmaceuticals Inc.

Schizophrenia

Recruiting

Study of evenamide as add-on treatment for patients with treatment-resistant schizophrenia not adequately controlled by current antipsychotic medications

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Sponsor:Newron Pharmaceuticals S.p.A.

Study on the Effects of Baxdrostat and Dapagliflozin in Adults with Chronic Kidney Disease and High Blood Pressure

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:AstraZeneca AB

Study on the Effects of Ferric Carboxymaltose on Heart Health and Quality of Life in Patients with Recent Heart Attack and Iron Deficiency

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Agencja Badań Medycznych

Study on Clazakizumab for Heart Disease in Adults with End-Stage Kidney Disease on Dialysis

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Clazakizumab
  • Sponsor:CSL Behring LLC

Study on the Effectiveness of Abelacimab for High-Risk Atrial Fibrillation Patients Unsuitable for Oral Anticoagulation

Investigational
Countries:PolandPoland
  • Participants:65+ years
  • Substances:Abelacimab
  • Sponsor:Anthos Therapeutics Inc.

A study of rilvegostomig, cisplatin, and gemcitabine compared to durvalumab and a drug combination for adults with advanced biliary tract cancer

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Cisplatin
  • Sponsor:AstraZeneca AB
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Zigakibart
  • Sponsor:Novartis Pharma AG
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