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Sahlgrenska University Hospital-Vastra Gotalandsregionen

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Sweden Bla Straket 5, 413 46 Gothenburg, Sweden

  • 22 trials recruiting
  • Chronic obstructive pulmonary disease · Cystic fibrosis · Adenocarcinoma pancreas
  • Adults and children

About Specializations

Sahlgrenska University Hospital-Vastra Gotalandsregionen in Gothenburg, Sweden specialises in clinical trials of conditions such as Chronic obstructive pulmonary disease, Cystic fibrosis, Adenocarcinoma pancreas, Atrial fibrillation, and other specialisations. This site conducts important research.

Main research areas of the site

Urology and Male Urogenital Diseases

At Sahlgrenska University Hospital-Vastra Gotalandsregionen in Gothenburg, clinical research in urology focuses strongly on prostate cancer and urothelial cancer, with studies also addressing biochemical recurrence after surgery and advanced disease. These trials are designed to improve treatment effectiveness, refine imaging-guided care, and support better long-term cancer control.

  • Prostate cancer and biochemical recurrence after surgery
  • Urothelial cancer and other genitourinary malignancies
  • Testing treatment strategies that may improve survival and reduce recurrence

The site’s urology program reflects a broad interest in both localized and advanced genitourinary cancers, combining patient-centered care with research aimed at more precise and effective treatment choices.

Neoplasms and Oncology Research

A major part of the research portfolio at this hospital involves cancer studies across several therapeutic areas, including breast cancer, melanoma, lung cancer, pancreatic cancer, and colorectal cancer. The trials are largely focused on evaluating new therapies, comparing treatment combinations, and improving outcomes for patients with advanced or high-risk disease.

  • Advanced solid tumors and metastatic cancer
  • Breast, melanoma, lung, pancreatic, and colon cancers
  • Assessing new immunotherapy and targeted treatment approaches

This oncology activity highlights a strong commitment to improving survival, disease control, and personalized treatment selection for people with a wide range of malignant tumors.

Cardiovascular Diseases and Stroke Prevention

The site is also active in cardiovascular research, with studies in atrial fibrillation, heart failure, Takotsubo syndrome, and pulmonary arterial hypertension. Several trials aim to prevent stroke and systemic embolism, improve rhythm control, and evaluate treatments that may reduce hospitalizations and other serious complications.

  • Atrial fibrillation and stroke prevention
  • Heart failure and pulmonary arterial hypertension
  • Testing therapies to improve cardiovascular outcomes and safety

These studies show a clear emphasis on both common and complex heart and vascular disorders, with research designed to support safer and more effective long-term management.

Respiratory Tract Diseases and Chronic Obstructive Pulmonary Disease

In the field of respiratory medicine, trials at this site include COPD, cystic fibrosis, and pulmonary fibrosis-related conditions. The research is aimed at easing symptoms, lowering exacerbation rates, and improving lung function and overall quality of life for people living with chronic respiratory illness.

  • Chronic obstructive pulmonary disease and frequent exacerbations
  • Cystic fibrosis and rare mutation-related disease
  • Evaluating treatments that may improve breathing and disease stability

This work reflects ongoing efforts to advance care for chronic lung diseases through better symptom control and more durable treatment benefit.

Nervous System Diseases and Mental Disorders

Research in neurology and psychiatry includes studies in acute ischemic stroke, epilepsy, Parkinson’s disease, multiple sclerosis, and major depressive disorder. The main goals are to improve recovery after neurologic events, slow disease progression, and test new options for mood-related conditions, including cancer-related depression.

  • Stroke recovery and stroke prevention
  • Epilepsy, Parkinson’s disease, and multiple sclerosis
  • Evaluating new treatments for neurologic and psychiatric conditions

This broad portfolio shows active investigation into both brain disorders and mental health, with a focus on practical improvements in daily functioning and long-term outcomes.

Immune System Diseases and Inflammatory Conditions

The site also conducts trials in immune-mediated diseases such as atopic dermatitis, Sjögren’s syndrome, and systemic sclerosis. These studies are intended to assess whether new therapies can better control inflammation, reduce symptoms, and improve patient comfort in chronic autoimmune and skin conditions.

  • Atopic dermatitis and other inflammatory skin disease
  • Sjögren’s syndrome and systemic sclerosis
  • Testing therapies that may improve immune-related disease control

This area of research supports a wider effort to improve care for autoimmune disorders that can affect the skin, glands, and connective tissues.

Female Urogenital Diseases and Reproductive Health

Clinical trials in this area include studies of ectopic pregnancy, preeclampsia, and labour induction. The research is focused on improving maternal and pregnancy outcomes, while also exploring safer and more effective ways to manage common obstetric complications.

  • Ectopic pregnancy and treatment options
  • Preeclampsia and pregnancy prolongation strategies
  • Evaluating safer approaches to labour induction

These studies show that the site contributes not only to urologic research but also to important women’s health questions in reproductive medicine.

Hemic and Lymphatic Diseases

The research portfolio includes studies in myelodysplastic syndrome, multiple myeloma, chronic lymphocytic leukemia, and lymphoma. These trials are generally aimed at improving disease control, reducing transfusion needs, and finding better treatment options for blood cancers and related disorders.

  • Myelodysplastic syndrome and anemia management
  • Multiple myeloma, lymphoma, and chronic lymphocytic leukemia
  • Testing therapies to improve blood cancer outcomes and supportive care

This work adds another important dimension to the site’s broader oncology and hematology activity.

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Site location
Bla Straket 5413 46 GothenburgSweden
Recruiting now
22 trials
Conditions studied
55
Partner status
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Ongoing trials

Clinical trials currently enrolling participants at this site.

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59 clinical trials

Study on the Effectiveness and Safety of Deucravacitinib for Adults with Active Sjogren's Syndrome

Investigational
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Deucravacitinib
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Comparing sotorasib and pembrolizumab with chemotherapy for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Amgen Inc.

Study on Long-Term Safety of Tolebrutinib and Teriflunomide for Patients with Multiple Sclerosis

Registered drug
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Teriflunomide
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Liposarcoma+2

Recruiting

Study of Pemigatinib and Retifanlimab for Patients with Advanced Dedifferentiated Liposarcoma

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Pemigatinib
  • Sponsor:Region Skane

Breast cancer

Recruiting

Study on Extended Endocrine Therapy for High-Risk Breast Cancer Patients Using Tamoxifen, Exemestane, Anastrozole, and Letrozole

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Region Oerebro Laen

Induced labour+1

Recruiting

Study on Misoprostol for Inducing Labor in Pregnant Women: Comparing Outpatient and Inpatient Settings

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years
  • Substances:Misoprostol
  • Sponsor:University Of Gothenburg

Study on Montelukast for Slowing Parkinson's Disease Progression in Patients with Mild to Moderate Symptoms

Registered drug
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Levodopa
  • Sponsor:Karolinska University Hospital

Study on Psilocybin for Treating Depression in Cancer Patients

InvestigationalNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Psilocybine
  • Sponsor:Region Stockholm – SLSO
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Lutetium (177LU) vipivotide tetraxetan
  • Sponsor:Novartis Pharma AG

Study Comparing Telisotuzumab Vedotin and Docetaxel for Adults with Previously Treated Non-Squamous Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Study on the Effectiveness and Safety of Lifileucel and Pembrolizumab for Patients with Untreated, Unresectable, or Metastatic Melanoma

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Aldesleukin
  • Sponsor:Iovance Biotherapeutics Inc.

Study on the Effects of Adenosine, Dipyridamole, and Apixaban in Patients with Takotsubo Syndrome

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Adenosine
  • Sponsor:Vaestra Goetalandsregionen
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