Rigshospitalet

At Rigshospitalet, the Department of Neurology and Danish Headache Center are involved in studies across nervous system diseases and related pain conditions, with a strong focus on finding better ways to relieve symptoms and improve daily function.

• Trigeminal neuralgia and diabetic neuropathic pain, with trials assessing whether new treatments can reduce severe nerve pain more effectively
• Coma and other disorders of consciousness after brain injury, exploring approaches that may support recovery of awareness and responsiveness
• Relapsing-remitting multiple sclerosis, studying therapies aimed at controlling disease activity and improving treatment options

These trials reflect a broad effort to advance care in complex neurological conditions, from pain management to recovery after acute brain injury.

The site also supports research in eye diseases, with studies designed to improve treatment for conditions that can threaten vision and quality of life.

• Fuchs endothelial corneal dystrophy, evaluating new options to support corneal health and visual recovery
• Geographic atrophy, testing therapies intended to slow the worsening of retinal damage
• Open-angle glaucoma and ocular hypertension, focusing on better control of eye pressure and longer-lasting treatment effects
• Atopic keratoconjunctivitis, examining whether a topical therapy can improve inflammation and eye discomfort

Much of this work aims to improve both symptom control and long-term preservation of sight.

Clinical studies in musculoskeletal diseases at Rigshospitalet include inflammatory conditions where researchers are comparing treatment strategies to help patients achieve better disease control.

• Rheumatoid arthritis, with trials examining how conventional care compares with biologic therapies and treatment adjustment strategies

This research is centered on improving symptom relief, reducing inflammation, and identifying approaches that may lead to more durable remission.

In the area of cardiovascular diseases, the site is contributing to research aimed at lowering the risk of recurrent stroke after a recent ischemic event.

• Prevention of ischemic stroke after acute non-cardioembolic stroke or high-risk transient ischemic attack, testing whether a new treatment strategy can better protect patients from another event

These trials are focused on improving secondary prevention and strengthening long-term vascular protection.

Studies linked to nutritional and metabolic diseases at the site often overlap with pain and neurological care, reflecting the complex ways chronic illness can affect patients.

• Diabetic neuropathic pain, investigating whether a new approach can ease persistent lower-extremity pain
• Menstrual migraine, evaluating a treatment intended to prevent attacks during the menstrual cycle

These projects aim to improve day-to-day symptom control for people living with long-term metabolic and headache-related conditions.