Digestive System Diseases

At Radboud universitair medisch centrum the Surgery department leads studies on severe acute pancreatitis, aiming to curb the high risk of organ failure and death through early intervention.

  • Early intravenous Omega-3 fatty acid therapy
  • Modulation of hyperinflammation in acute pancreatitis
  • Reducing intensive care stay and hospital costs

The research evaluates whether Omega-3 fatty acids can improve clinical outcomes, lower mortality, and enhance quality of life for patients with predicted severe disease.

Neoplasms

Investigations focus on HER2-low and HER2 IHC0 breast cancer, a challenging subgroup of neoplasms that often lack effective targeted options.

  • Antibody‑drug conjugate therapy with T-DXd
  • Evaluating time to next treatment as a measure of benefit
  • Inclusion of hormone receptor‑negative and positive patient cohorts

The goal is to assess the potential of T-DXd to extend disease control and provide new therapeutic avenues for patients with advanced HER2‑low breast cancer.