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Premedix

Research site

Slovakia Jelsova 3086/1, 831 01 Bratislava, Slovakia

  • 5 trials recruiting
  • Cardiovascular disorder · Hypertension · Type 2 diabetes mellitus
  • Adult patients

About Specializations

Premedix in Bratislava, Slovakia specialises in clinical trials of conditions such as Cardiovascular disorder, Hypertension, Type 2 diabetes mellitus, Arteriosclerosis, and other specialisations. This site conducts important research.

Main research areas of the site

Heart Failure & Reduced Ejection Fraction

The Cardiology Clinic at Premedix is conducting studies aimed at improving outcomes for patients with heart failure and reduced ejection fraction.

  • Testing novel agents to lower cardiac stress markers.
  • Evaluating combination therapy to prevent hospitalization.
  • Comparing new treatments against standard care for mortality reduction.

These trials seek to bring safer, more effective options to individuals living with advanced heart failure in Bratislava.

Inherited and Elevated Lipid Disorders

Research at Premedix focuses on managing high LDL‑C and elevated Lp(a) levels that drive atherosclerotic disease.

  • Assessing the impact of a targeted therapy on LDL‑C reduction.
  • Exploring treatment for patients with heterozygous familial hypercholesterolemia.
  • Investigating agents that lower Lp(a) to decrease major cardiovascular events.

The goal is to provide patients with better lipid control and lower risk of heart attacks and strokes.

Diabetes, Hypertension and Cardiovascular Risk

The site is evaluating strategies that address the combined burden of type 2 diabetes, high blood pressure and existing cardiovascular disease.

  • Testing a dual therapy to reduce cardiovascular death and hospitalizations.
  • Measuring the effect of new drugs on major adverse cardiovascular events.
  • Studying how metabolic control influences heart failure outcomes.

By targeting multiple risk factors, these studies aim to improve long‑term health for patients with complex cardiometabolic profiles.

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Site location
Jelsova 3086/1831 01 BratislavaSlovakia
Recruiting now
5 trials
Conditions studied
10

More sites in BratislavaSlovakia

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

10 clinical trials

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Substances:Zilebesiran
  • Sponsor:Alnylam Pharmaceuticals Inc.

Study of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease

Registered drug
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Substances:BI 690517
  • Sponsor:Boehringer Ingelheim Espana S.A.

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Sponsor:AstraZeneca AB

Effect of elecoglipron plus dapagliflozin on cardiovascular outcomes in adults with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF)

Registered drug
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

Cardiac failure

Recruiting

Evaluating the Effect of Vicadrostat and Empagliflozin Combination Compared to Empagliflozin Alone in Patients with Heart Failure and Reduced Left Ventricular Function

Registered drug
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Substances:BI 690517
  • Sponsor:Boehringer Ingelheim International GmbH

Type 2 diabetes mellitus+2

Not yet recruiting

Effect of lenbelintide (AZD6234) on body weight in adults with type 2 diabetes and obesity or overweight

Investigational
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Substances:AZD6234
  • Sponsor:AstraZeneca AB

Arteriosclerosis

Not yet recruiting

A study to evaluate the effect of muvalaplin on reducing major cardiovascular events in adults with high levels of lipoprotein(a) and atherosclerotic cardiovascular disease.

Investigational
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Sponsor:Eli Lilly & Co.

Evaluating the efficacy and safety of CRD-4730 in patients with heart failure with reduced ejection fraction

Investigational
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Substances:CRD-4730
  • Sponsor:Cardurion Pharmaceuticals Inc.

Study of laroprovstat (AZD0780) tablets to lower cholesterol levels in adults with inherited high cholesterol condition (heterozygous familial hypercholesterolemia)

Investigational
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Sponsor:AstraZeneca AB

Study on the Safety and Effectiveness of Tovinontrine for Adults with Chronic Heart Failure with Reduced Ejection Fraction

Investigational
Countries:SlovakiaSlovakia
  • Participants:18–64 years · 65+ years
  • Substances:Tovinontrine
  • Sponsor:Cardurion Pharmaceuticals Inc.
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