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Pole Vision Val D'Ouest

Research site

France 39 Chemin De La Vernique, 69130 Ecully, France

  • 4 trials recruiting
  • Dry age-related macular degeneration · Age-related macular degeneration · Neovascular age-related macular degeneration
  • Adult patients

About Specializations

Pole Vision Val D'Ouest in Ecully, France specialises in clinical trials of conditions such as Dry age-related macular degeneration, Age-related macular degeneration, Neovascular age-related macular degeneration, Choroidal neovascularisation, and other specialisations. This site conducts important research.

Main research areas of the site

Eye Diseases Research

At Pole Vision Val D'Ouest, the Department of Ophthalmology is running clinical studies focused on eye diseases, especially conditions that threaten central vision and long-term sight. The research is centered on improving treatment options, protecting visual function, and slowing disease progression in patients with chronic retinal and optic nerve disorders.

  • Studies in geographic atrophy and age-related macular degeneration are exploring ways to slow retinal damage and preserve vision.
  • Research in neovascular age-related macular degeneration and choroidal neovascularization is evaluating better control of abnormal blood vessel growth and treatment response.
  • Trials in diabetic macular oedema are assessing new approaches to improve visual outcomes in diabetes-related eye disease.
  • Work in open-angle glaucoma and ocular hypertension is aimed at better pressure control and longer-lasting eye pressure reduction.
  • Additional studies in central retinal vein occlusion are looking at vision recovery and factors that influence prognosis.

Overall, the site’s trial portfolio reflects a strong focus on retinal degeneration, macular disease, and glaucoma, with research designed to test new therapies, improve disease management, and support better long-term vision care.

Retinal Degeneration and Macular Disease

A major part of the clinical research at this site involves progressive retinal conditions, including geographic atrophy, dry age-related macular degeneration, and neovascular age-related macular degeneration. These studies are designed to understand whether new treatments can slow tissue loss, reduce disease activity, and help maintain reading and central vision.

  • Studies in geographic atrophy secondary to AMD are testing strategies to reduce lesion growth and preserve retinal structure.
  • Research in dry AMD with geographic atrophy is focused on protecting visual function in advanced macular degeneration.
  • Trials in neovascular AMD are evaluating whether newer therapies can improve control of the disease and support better sight.
  • Work in pathologic myopia is examining treatment options for vision loss caused by abnormal choroidal vessels.

These studies highlight a clear emphasis on finding more effective ways to manage degenerative macular disorders and limit the impact of irreversible vision loss.

Glaucoma and Ocular Hypertension Research

The site also contributes to studies in glaucoma care, with a focus on open-angle glaucoma and ocular hypertension. The goal is to improve eye pressure control, evaluate durability of benefit, and support long-term protection of the optic nerve.

  • Research in open-angle glaucoma is examining treatments that may help lower pressure more effectively over time.
  • Studies in ocular hypertension are assessing whether new options can reduce the risk of progression to glaucoma.
  • Trials are also looking at how long treatment effects last, with the aim of making care more convenient and sustained.

This area of research is important for preventing gradual vision loss and supporting earlier, more reliable disease control in patients at risk of optic nerve damage.

Retinal Vascular and Vision Function Studies

Another theme at Pole Vision Val D'Ouest is research on retinal vascular disease, especially central retinal vein occlusion. These studies are intended to better understand changes in vision over time and to evaluate how treatment can influence recovery and long-term outcomes.

  • Studies in central retinal vein occlusion are comparing visual improvement in different patient groups.
  • Research is also assessing how retinal circulation and vascular changes relate to prognosis and treatment response.
  • Some trials are focused on measuring visual function and visual acuity as key indicators of benefit.

This work supports a more precise approach to managing retinal vein disorders and understanding which patients may benefit most from treatment.

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Site location
39 Chemin De La Vernique69130 EcullyFrance
Recruiting now
4 trials
Conditions studied
7

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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13 clinical trials

A Phase 2/3 Study of intravitreal mk-8748 versus aflibercept in adults with neovascular age‑related macular degeneration

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Aflibercept
  • Sponsor:Eyebiotech Limited

Study of Surabgene Lomparvovec Compared to Ranibizumab for Adults with Wet Age-Related Macular Degeneration

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Ranibizumab
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Study of Pozelimab and Cemdisiran for Adults with Geographic Atrophy from Age-Related Macular Degeneration

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Cemdisiran
  • Sponsor:Regeneron Pharmaceuticals Inc.

Study on Tinlarebant for Treating Geographic Atrophy in Patients

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Tinlarebant
  • Sponsor:Belite Bio Inc.

Faricimab for Choroidal Neovascularization Secondary to Pathologic Myopia in Patients with Pathologic Myopia

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Faricimab
  • Sponsor:F. Hoffmann-La Roche AG

Study on the Effectiveness and Safety of ANX007 Injections for Patients with Geographic Atrophy from Age-Related Macular Degeneration

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:ANX007
  • Sponsor:Annexon Inc.
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Dexamethasone
  • Sponsor:Hospices Civils De Lyon

Study on the Effectiveness of OPT-302 and Ranibizumab for Patients with Wet Age-related Macular Degeneration

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Ranibizumab
  • Sponsor:Opthea Limited

Study on Long-Term Safety and Effects of Pegcetacoplan for Patients with Geographic Atrophy from Age-Related Macular Degeneration

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Pegcetacoplan
  • Sponsor:Apellis Pharmaceuticals Inc.

Study on the Effect of Aflibercept Injections in Patients with Central Retinal Vein Occlusion (CRVO) and Spontaneous Retinal Arterial Pulsations (SRAPs)

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Aflibercept
  • Sponsor:Fondation A De Rothschild

Study of Danicopan for Patients with Geographic Atrophy Due to Age-Related Macular Degeneration

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Danicopan
  • Sponsor:Alexion Pharmaceuticals Inc.

Open angle glaucoma+1

Not recruiting

Study on Long-term Safety and Effectiveness of Bimatoprost SR for Patients with Open-angle Glaucoma or Ocular Hypertension

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bimatoprost
  • Sponsor:AbbVie Deutschland GmbH & Co. KG
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