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Philipps-Universitaet Marburg

Verified siteinfo

Germany Baldingerstrasse, 35043 Marburg, Germany

  • 53 trials recruiting
  • Acute myeloid leukaemia · Conjunctivitis allergic · Oesophageal adenocarcinoma
  • Adults and children

About Specializations

Philipps-Universitaet Marburg in Marburg, Germany specialises in clinical trials of conditions such as Acute myeloid leukaemia, Conjunctivitis allergic, Oesophageal adenocarcinoma, Partial seizures, and other specialisations. This site conducts important research.

Main research areas of the site

Eye Diseases Research

The clinic focuses on eye diseases, investigating conditions such as macular edema due to central retinal vein occlusion and moderate-to-severe thyroid eye disease, with the goal of refining treatment protocols and reducing injection burden.

  • Ranibizumab injection optimization
  • Peripheral laser photocoagulation adjunct
  • Satralizumab efficacy in thyroid eye disease

Collaboration with Philipps-Universitaet Marburg enables multidisciplinary expertise and patient‑centered outcomes.

Hematologic & Lymphatic Oncology

Research in hematologic and lymphatic diseases targets acute myeloid leukemia, early‑stage unfavorable classical Hodgkin lymphoma, large B‑cell lymphoma, and MSI‑high colorectal cancer, aiming to improve survival through innovative cellular and immunotherapies.

  • CAR T cell therapy evaluation
  • Checkpoint inhibitor strategies
  • Lymphodepletion regimen optimization

With 50 investigators, the site advances precision oncology across multiple cancer types.

Immune‑Mediated Disorders

The department studies immune system diseases such as thyroid eye disease, employing novel biologics like satralizumab to assess efficacy and safety while seeking to lessen disease‑related disability.

  • Subcutaneous immunotherapy trials
  • Proptosis response assessment
  • Safety profiling of new biologics

As an educational institution, the site integrates clinical insight with academic research.

Prostate Cancer Studies

Investigations into prostate cancer focus on metastatic hormone‑sensitive disease, comparing docetaxel dosing schedules and combining chemotherapy with darolutamide plus androgen deprivation therapy to enhance progression‑free survival.

  • Docetaxel dosing comparisons
  • Combination with androgen deprivation therapy
  • Adverse event monitoring strategies

Commercial partnerships support the development of optimized therapeutic regimens.

Solid Tumor Investigations

The site addresses neoplasms including metastatic colorectal cancer, advanced HER2‑negative breast cancer, and melanoma, evaluating checkpoint inhibitors and combination regimens to extend overall survival and understand resistance patterns.

  • Subcutaneous nivolumab/relatlimab study
  • Combination immunotherapy trials
  • Molecular resistance analysis in breast cancer

A total of 11 clinical trials contribute to a comprehensive oncology portfolio.

Neurology Trials

Efforts in nervous system diseases concentrate on refractory status epilepticus, testing adjunctive IV ganaxolone added to standard antiepileptic drugs to improve seizure control and patient safety.

  • Adjunctive ganaxolone efficacy study
  • Safety assessment in acute seizures
  • Integration with standard of care protocols

The program aims to deliver faster, more effective interventions for life‑threatening seizures.

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Site location
Baldingerstrasse35043 MarburgGermany
Recruiting now
53 trials
Conditions studied
98
Partner status
Verified site

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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113 clinical trials

Crohn's disease

Recruiting

A study to evaluate the effectiveness and safety of duvakitug in patients with moderate to severe Crohn's disease

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

A study of duvakitug for patients with moderately to severely active ulcerative colitis to see if it works and is safe as maintenance therapy

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

A study testing duvakitug for patients with moderately to severely active ulcerative colitis

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Uveal melanoma

Recruiting

A Study of Darovasertib Before Surgery or Radiation Therapy for Patients with Early-Stage Uveal Melanoma That Has Not Spread

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Darovasertib
  • Sponsor:Ideaya Biosciences Inc.

A Study of Ivonescimab Combined with Fluorouracil, Folinic Acid, and Oxaliplatin Compared to Bevacizumab for Patients with Metastatic Colorectal Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Summit Therapeutics Inc.

Study on the Safety of BHV-7000 for Adults with Hard-to-Treat Focal Onset Epilepsy

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:BHV-7000
  • Sponsor:Biohaven Therapeutics Ltd.

Study on the Effectiveness of PQ Grass for Children and Teens with Seasonal Allergies from Grass Pollen

Registered drug
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Desloratadine
  • Sponsor:Allergy Therapeutics (UK) Limited

Study on the Use of SYN2, Adenosine, and Regadenoson for Diagnosing Coronary Artery Disease in Patients with Suspected Heart Conditions

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Adenosine

A Phase 3 Study of Engasertib to Evaluate Safety and Effectiveness in Adults with Moderate to Severe Hereditary Hemorrhagic Telangiectasia

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Vaderis Therapeutics AG

Durvalumab plus drug combination as total neoadjuvant therapy for patients with resectable gastroesophageal adenocarcinoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbH

Gastric cancer+1

Recruiting

Study of AZD0901 (sonesitatug vedotin) with capecitabine ± rilvegostomig in adults with advanced stomach or esophageal cancer (Claudin‑18.2‑positive, HER2‑negative)

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:AZD0901
  • Sponsor:Astrazeneca AB

Crohn's disease

Recruiting

Study of mirikizumab versus azathioprine in newly diagnosed moderate-to-severe Crohn’s disease patients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Azathioprine
  • Sponsor:Universitaetsklinikum Schleswig-Holstein AöR
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