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Orszagos Onkologiai Intezet

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Hungary Rath Gyorgy Utca 7-9, Kerulet, 1122 Budapest, Hungary

  • 62 trials recruiting
  • Non-small cell lung cancer · Breast cancer · Endometrial cancer
  • Adults and children

About Specializations

Orszagos Onkologiai Intezet in Budapest, Hungary specialises in clinical trials of conditions such as Non-small cell lung cancer, Breast cancer, Endometrial cancer, Hormone-refractory prostate cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Non-Small Cell Lung Cancer (NSCLC)

The medical center is at the forefront of research in Non-Small Cell Lung Cancer, focusing on innovative therapies that target specific biomarkers and genetic mutations. The center's research aims to improve treatment outcomes for patients with advanced stages of NSCLC.

  • PD-L1 high NSCLC
  • ALK-positive NSCLC
  • HER2 mutations in NSCLC

By exploring novel drug combinations and personalized medicine approaches, the center contributes significantly to the advancement of NSCLC treatment strategies.

Prostate Cancer

Specializing in biochemically recurrent prostate cancer, the center conducts pivotal studies to enhance therapeutic options for patients at high risk of recurrence. The research focuses on combining androgen deprivation therapy with novel agents to improve patient outcomes.

  • Androgen deprivation therapy (ADT)
  • PSA marker analysis

Through these studies, the center aims to refine treatment protocols and extend progression-free survival for prostate cancer patients.

Renal Cell Carcinoma (RCC)

The center is a leader in the study of Renal Cell Carcinoma, focusing on immune and targeted combination therapies. Research efforts are directed towards improving safety and efficacy profiles of new treatment regimens.

  • Advanced RCC therapies
  • Combination treatment strategies

By evaluating novel drug combinations, the center seeks to enhance the therapeutic landscape for RCC patients.

Lymphoma

Research at the center includes a strong focus on lymphoma, particularly follicular lymphoma and diffuse large B-cell lymphoma. The center explores innovative treatment combinations to improve patient outcomes in relapsed or refractory cases.

  • Follicular Lymphoma (FL)
  • Diffuse Large B-Cell Lymphoma (DLBCL)

These studies aim to develop more effective therapeutic options and improve survival rates for lymphoma patients.

Breast Cancer

The center is dedicated to advancing treatment for breast cancer, with a focus on hormone receptor-positive and HER2-negative subtypes. Research includes evaluating new drug combinations and assessing their impact on progression-free survival.

  • ER+/HER2- Breast Cancer
  • Metastatic Breast Cancer

Through these efforts, the center aims to provide more personalized and effective treatment options for breast cancer patients.

Endometrial Cancer

Focusing on endometrial cancer, the center conducts research to evaluate the efficacy of novel immunotherapy combinations. The goal is to improve progression-free survival and overall survival in patients with advanced or recurrent disease.

  • Advanced Endometrial Cancer
  • Recurrent Endometrial Cancer

These studies aim to enhance treatment protocols and offer new hope for endometrial cancer patients.

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Site location
Rath Gyorgy Utca 7-9, Kerulet1122 BudapestHungary
Recruiting now
62 trials
Conditions studied
108

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Ongoing trials

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169 clinical trials

Phase 3 Study of atebimetinib with gemcitabine and paclitaxel versus gemcitabine and paclitaxel in patients with metastatic pancreatic cancer

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Paclitaxel

A Phase 3 Randomized Study of mRNA‑4157 plus Pembrolizumab as Adjuvant Therapy in Patients with Completely Resected Stage I Non‑Small Cell Lung Cancer

Investigational
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:MRNA-4157
  • Sponsor:Merck Sharp & Dohme LLC

A study of loxo-435, enfortumab vedotin, and pembrolizumab in adults with advanced or metastatic bladder cancer

Registered drug
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Enfortumab Vedotin
  • Sponsor:Eli Lilly & Co.

Study of sotorasib, panitumumab and a drug combination for patients with metastatic colorectal cancer with KRAS p.G12C mutation.

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years
  • Substances:Bevacizumab
  • Sponsor:Amgen Inc.

Phase III Randomized Study of Rilvegostomig vs. Pembrolizumab with Platinum-based Chemotherapy in PD-L1 Expressing Metastatic Squamous NSCLC

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:AstraZeneca AB

A Study of Ivonescimab Combined with Fluorouracil, Folinic Acid, and Oxaliplatin Compared to Bevacizumab for Patients with Metastatic Colorectal Cancer

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Summit Therapeutics Inc.

Colorectal cancer+1

Recruiting

Study of NGM120 in patients with colorectal cancer and cancer cachexia: Evaluating effects on body weight

Investigational
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:HUMANISED IGG1 MONOCLONAL ANTIBODY AGAINST GDNF FAMILY RECEPTOR ALPHA-LIKE
  • Sponsor:Ngm Biopharmaceuticals Inc.

Study on the Safety and Effectiveness of BNT327 with Chemotherapy for Patients with Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:BNT327
  • Sponsor:BioNTech SE

Study comparing rilvegostomig plus chemotherapy versus pembrolizumab plus chemotherapy for first-line treatment in patients with metastatic non-squamous lung cancer with PD-L1 expression

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:AstraZeneca AB

Study on the Long-term Safety and Efficacy of Pembrolizumab and Lenvatinib for Patients with Advanced Tumors

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Favezelimab
  • Sponsor:Merck Sharp & Dohme LLC

Study of LY3537982, pembrolizumab, and a drug combination for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drug
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Eli Lilly & Co.

Rinatabart Sesutecan with or without bevacizumab versus standard platinum‑based chemotherapy drug combination in patients with recurrent platinum‑sensitive ovarian cancer

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Genmab A/S
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