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Oncoradio Centre Oncogard

Research site

France Rue Du Professeur Henri Pujol Institut De Cancerologie, 30029 Nimes, France

  • 12 trials recruiting
  • Hormone receptor positive HER2 negative breast cancer · Ovarian epithelial cancer · Breast cancer metastatic
  • Adult patients

About Specializations

Oncoradio Centre Oncogard in Nimes, France specialises in clinical trials of conditions such as Hormone receptor positive HER2 negative breast cancer, Ovarian epithelial cancer, Breast cancer metastatic, Endometrial cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Digestive System Diseases

Research at Oncoradio Centre Oncogard targets cancers of the digestive tract, aiming to improve treatment effectiveness. Ovarian cancer trials explore new chemotherapy schedules and immunotherapy combinations. Colorectal cancer studies focus on adjuvant strategies for older patients.

  • Dose-dense chemotherapy regimens
  • Combination of PARP inhibitor with immunotherapy
  • Biomarker-driven patient selection
  • Neoadjuvant strategies for advanced disease

The site collaborates in multinational studies and emphasizes personalized medicine to tailor therapies for individual patients.

Hemic and Lymphatic Diseases

Investigations include blood‑related malignancies, seeking to expand therapeutic options. Acute myeloid leukemia research evaluates novel targeted agents. Myelofibrosis projects assess combination approaches after JAK‑inhibitor failure. Multiple myeloma work examines MRD‑adapted treatment intensification.

  • Targeted therapies for high‑risk myelodysplastic syndrome
  • Novel JAK‑inhibitor combinations
  • Antibody‑drug conjugates for leukemia
  • MRD‑guided treatment adaptation

These efforts reflect a commitment to clinical innovation in hematologic oncology.

Male Urogenital Diseases

The department conducts trials on cancers affecting the male urogenital tract. Prostate cancer studies test radioligand therapy and intensified androgen deprivation. Penile carcinoma investigations compare surgical and chemotherapeutic approaches.

  • Radioligand therapy for metastatic castration‑resistant prostate cancer
  • Combination of androgen deprivation with novel agents
  • Surgical and chemotherapeutic approaches for penile cancer
  • Biomarker-driven de‑escalation strategies

The program prioritizes patient‑centered care and multidisciplinary coordination.

Neoplasms

A broad portfolio addresses solid tumors, with emphasis on innovative systemic therapies. Breast cancer research spans HER2‑positive de‑escalation, ER+/HER2‑low evaluation, and CDK4/6 inhibitor sequencing. Endometrial cancer trials explore immunotherapy combinations for high‑risk disease.

  • HER2‑targeted de‑escalation trials
  • ER+/HER2‑low therapeutic evaluation
  • CDK4/6 inhibitor sequencing after endocrine resistance
  • Immunotherapy in triple‑negative breast cancer

The centre integrates advanced diagnostics to refine patient selection and outcome measurement.

Pathological Conditions, Signs and Symptoms

Studies focus on molecular markers that guide treatment decisions. Circulating tumor DNA is used to trigger early therapy switches, while minimal residual disease status informs transplant and maintenance strategies.

  • ctDNA‑guided treatment switches
  • MRD‑adapted transplant strategies
  • Biomarker integration in trial design
  • Safety monitoring of novel agents

This work exemplifies a move toward precision oncology across multiple tumor types.

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Site location
Rue Du Professeur Henri Pujol Institut De Cancerologie30029 NimesFrance
Recruiting now
12 trials
Conditions studied
27

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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26 clinical trials

Comparing AZD5335 with mirvetuximab soravtansine or a drug combination in patients with platinum-resistant ovarian cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD5335
  • Sponsor:AstraZeneca AB

A Study of Puxitatug Samrotecan Compared to Chemotherapy for Patients with Advanced Endometrial Cancer After Previous Platinum and Immunotherapy Treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD8205
  • Sponsor:AstraZeneca AB

Prostate cancer

Recruiting

A study of saruparib with radiotherapy and hormone therapy for men with high-risk prostate cancer who have a BRCA gene mutation

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone Acetate
  • Sponsor:AstraZeneca AB

Study on the Effectiveness and Safety of Tagraxofusp and Venetoclax for Adults with Untreated Blastic Plasmacytoid Dendritic Cell Neoplasm

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Tagraxofusp
  • Sponsor:French Innovative Leukemia Organization (F.I.L.O.).

Study on Pembrolizumab for Patients with Early Triple-Negative Breast Cancer Responding Well to Initial Treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Unicancer

Study on Re-treatment with Lutetium (177Lu) Vipivotide Tetraxetan for Men with Metastatic Castration-Resistant Prostate Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Gozetotide
  • Sponsor:Hospices Civils De Lyon

Peritoneal sarcoma+5

Recruiting

Study on Adjusting Chemotherapy with Carboplatin and Paclitaxel for Patients with Poor Prognostic Ovarian Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Arcagy Gineco

Penile cancer

Recruiting

Study on the Effects of Chemotherapy with Paclitaxel, Ifosfamide, and Cisplatin for Patients with Squamous Cell Carcinoma of the Penis and Lymph Node Metastasis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Aprepitant
  • Sponsor:Unicancer

Study of Fluoroestradiol F-18 and Biomarkers for Women with ER-Positive HER2-Negative Metastatic Breast Cancer After CDK4/6 Inhibitor Therapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Fluoroestradiol F-18
  • Sponsor:Institut Curie
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:AstraZeneca AB

Endometrial cancer+2

Recruiting

Study on Dostarlimab and Niraparib for Patients with Metastatic or Recurrent Endometrial or Ovarian Carcinosarcoma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Dostarlimab
  • Sponsor:Arcagy Gineco

Study on Reducing Treatment for Patients with HER2-Positive Metastatic Breast Cancer Using Trastuzumab and Drug Combination After 2 Years of Controlled Disease

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Pertuzumab
  • Sponsor:Unicancer
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